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从欧洲视角看太空环境中的人类发育与生殖

Human development and reproduction in space-a European perspective.

作者信息

Jain Varsha, Chuva de Sousa Lopes Susana M, Benotmane Mohammed A, Verratti Vittore, Mitchell Rod T, Stukenborg Jan-Bernd

机构信息

MRC Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.

Department of Anatomy and Embryology, Leiden University Medical Center (Building 2), Leiden, The Netherlands.

出版信息

NPJ Microgravity. 2023 Mar 27;9(1):24. doi: 10.1038/s41526-023-00272-5.

Abstract

This review summarises key aspects of the first reproductive and developmental systems Science Community White Paper, supported by the European Space Agency (ESA). Current knowledge regarding human development and reproduction in space is mapped to the roadmap. It acknowledges that sex and gender have implications on all physiological systems, however, gender identity falls outside the scope of the document included in the white paper collection supported by ESA. The ESA SciSpacE white papers on human developmental and reproductive functions in space aim to reflect on the implications of space travel on the male and female reproductive systems, including the hypothalamic-pituitary-gonadal (HPG) reproductive hormone axis, and considerations for conception, gestation and birth. Finally, parallels are drawn as to how this may impact society as a whole on Earth.

摘要

本综述总结了由欧洲航天局(ESA)支持的首份生殖与发育系统科学共同体白皮书的关键内容。目前关于太空人类发育与生殖的知识已被映射到路线图中。它承认性别对所有生理系统都有影响,然而,性别认同不在ESA支持的白皮书系列文件的范围内。ESA关于太空人类发育和生殖功能的SciSpacE白皮书旨在思考太空旅行对男性和女性生殖系统的影响,包括下丘脑 - 垂体 - 性腺(HPG)生殖激素轴,以及对受孕、妊娠和分娩的考量。最后,还探讨了这可能如何对地球上的整个社会产生影响。

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Semin Cell Dev Biol. 2022 Nov;131:58-65. doi: 10.1016/j.semcdb.2022.03.035. Epub 2022 Apr 14.
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Human placental development and function.人类胎盘的发育和功能。
Semin Cell Dev Biol. 2022 Nov;131:66-77. doi: 10.1016/j.semcdb.2022.03.039. Epub 2022 Apr 4.
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Albumin, oral contraceptives, and venous thromboembolism risk in astronauts.宇航员的白蛋白、口服避孕药和静脉血栓栓塞风险。
J Appl Physiol (1985). 2022 May 1;132(5):1232-1239. doi: 10.1152/japplphysiol.00024.2022. Epub 2022 Apr 7.
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Female astronauts: Impact of space radiation on menopause.女性宇航员:太空辐射对更年期的影响。
Eur J Obstet Gynecol Reprod Biol. 2022 Apr;271:210-213. doi: 10.1016/j.ejogrb.2022.02.022. Epub 2022 Feb 24.
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Development of mouse preimplantation embryos in space.小鼠植入前胚胎在太空的发育
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