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甲状腺对青春期前、青春期及成年大鼠睾丸脂质的作用。I. 甲状腺功能亢进

Role of thyroid on testicular lipids in prepubertal, pubertal and adult rats. I. Hyperthyroidism.

作者信息

Aruldhas M M, Valivullah H M, Srinivasan N, Govindarajulu P

出版信息

Biochim Biophys Acta. 1986 May 2;881(3):462-9. doi: 10.1016/0304-4165(86)90040-1.

Abstract

The influence of thyroxine-induced hyperthyroidism on testicular neutral and phospholipids was studied in prepubertal, pubertal and adult rats. Thyroxine treatment (25 micrograms/100 g body weight) for 1 month decreased testicular total lipids, total glyceride glycerols, total cholesterol and total phospholipids. Different classes of glyceride glycerol, cholesterol and phospholipid were also diminished due to thyroxine treatment. All classes of lipids returned to the euthyroid level after the withdrawal of thyroxine treatment. The data obtained in the present study suggest that thyroid hormones have a definite influence on testicular lipid metabolism in rats.

摘要

在青春期前、青春期和成年大鼠中研究了甲状腺素诱导的甲状腺功能亢进对睾丸中性脂质和磷脂的影响。用甲状腺素(25微克/100克体重)治疗1个月可降低睾丸总脂质、总甘油甘油酯、总胆固醇和总磷脂。由于甲状腺素治疗,不同类别的甘油甘油酯、胆固醇和磷脂也减少。停止甲状腺素治疗后,所有类别的脂质均恢复到甲状腺功能正常水平。本研究获得的数据表明,甲状腺激素对大鼠睾丸脂质代谢有明确影响。

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