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心脏结节病患者心尖部动脉瘤处持续性氟代脱氧葡萄糖摄取

Persistent FDG Uptake at Apical Aneurysm in a Patient With Cardiac Sarcoidosis.

作者信息

Rojulpote Chaitanya, Patil Shivaraj, Vidula Mahesh K, Kotloff Robert, Prenner Stuart, Bravo Paco E

机构信息

Division of Cardiovascular Imaging, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Department of Medicine, The Wright Center for Graduate Medical Education, Scranton, Pennsylvania, USA.

出版信息

JACC Case Rep. 2023 Mar 15;10:101763. doi: 10.1016/j.jaccas.2023.101763.

DOI:10.1016/j.jaccas.2023.101763
PMID:36974049
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10039390/
Abstract

We present a case of cardiac sarcoidosis with persistent, focal fluorodeoxyglucose uptake at the left ventricular apical aneurysm concerning for ongoing active inflammatory injury, prompting aggressive immunosuppressive therapy. This case highlights the importance of understanding the various clinical entities that may resemble disease activity on fluorodeoxyglucose positron emission tomography/computed tomography imaging. ().

摘要

我们报告一例心脏结节病患者,其左心室心尖部动脉瘤处存在持续性、局灶性氟脱氧葡萄糖摄取,提示存在持续的活动性炎性损伤,从而促使采取积极的免疫抑制治疗。该病例强调了在氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描成像中理解可能类似于疾病活动的各种临床实体的重要性。()

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5155/10039390/626b2c9a32a8/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5155/10039390/28c4f1abaf31/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5155/10039390/2448f2262034/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5155/10039390/e33c30125182/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5155/10039390/626b2c9a32a8/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5155/10039390/28c4f1abaf31/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5155/10039390/2448f2262034/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5155/10039390/e33c30125182/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5155/10039390/626b2c9a32a8/gr3.jpg

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本文引用的文献

1
Effect of Immunosuppressive Therapy and Biopsy Status in Monitoring Therapy Response in Suspected Cardiac Sarcoidosis.疑似心脏结节病的免疫抑制治疗和活检状态对监测治疗反应的影响。
JACC Cardiovasc Imaging. 2022 Nov;15(11):1944-1955. doi: 10.1016/j.jcmg.2022.05.015. Epub 2022 Aug 17.
2
PET Imaging in Cardiac Sarcoidosis: A Narrative Review with Focus on Novel PET Tracers.心脏结节病的正电子发射断层显像(PET):聚焦新型PET示踪剂的叙述性综述
Pharmaceuticals (Basel). 2021 Dec 9;14(12):1286. doi: 10.3390/ph14121286.
3
Series of myocardial FDG uptake requiring considerations of myocardial abnormalities in FDG-PET/CT.
一系列需要考虑 FDG-PET/CT 中心肌异常的心肌 FDG 摄取。
Jpn J Radiol. 2021 Jun;39(6):540-557. doi: 10.1007/s11604-021-01097-6. Epub 2021 Jan 31.
4
Left ventricular mural thrombus appearing as a photopenic defect on myocardial viability PET imaging.
J Nucl Cardiol. 2022 Oct;29(5):2713-2715. doi: 10.1007/s12350-020-02480-y. Epub 2021 Jan 5.
5
Joint SNMMI-ASNC Expert Consensus Document on the Role of F-FDG PET/CT in Cardiac Sarcoid Detection and Therapy Monitoring.SNMMI-ASNC关于F-FDG PET/CT在心脏结节病检测和治疗监测中作用的联合专家共识文件。
J Nucl Med. 2017 Aug;58(8):1341-1353. doi: 10.2967/jnumed.117.196287.