Department of Cardiovascular Medicine, the First Affiliated Hospital of Jinan University, Guangzhou, China.
Department of Cardiovascular Medicine Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
J Clin Hypertens (Greenwich). 2023 May;25(5):470-479. doi: 10.1111/jch.14622. Epub 2023 Mar 27.
The association of adiposity indices with prehypertension remains unclear in the Chinese non-hypertensive population. This study aimed to compare the association of adiposity indices, including waist circumference (WC), waist-to-height ratio, body roundness index (BRI), a body shape index (ABSI), and conicity index (CI), and prehypertension in the Chinese population. We recruited 61 475 participants from a population-based screening project in Guangdong province, China. Multiple logistic regression analyses were performed to detect the association between the six adiposity indices and prehypertension. Receiver operator characteristic curve (ROC) analysis was used to evaluate the predictive values of adiposity indices to prehypertension. The individuals were divided into two categories by blood pressure (BP) levels: normotension (<120/80 mmHg) and prehypertension (120-139/80-89 mmHg). A total of 33 233 people had prehypertension, with a prevalence of 54.04% and 42% males. Both logistics regression models presented a positive association between each adiposity index and prehypertension (p < .05), except for ABSI. The body mass index (BMI) was slightly more correlated with prehypertension than any other index. The standardized ORs for the six indices were 1.392, 1.361, 1.406, 1.039, 1.372, and 1.151, respectively. Compared to other adiposity indices, the WC had a significantly higher area under the curve (AUC) for predicting prehypertension (AUC: .619, sensitivity: 57%, specificity: 60.6%). In conclusion, WC and BMI might be the best indicators for prehypertension. Increasing evidence supports avoiding obesity as a preferred primary prevention strategy for prehypertension while controlling other major hypertension risk factors.
肥胖指数与中国非高血压人群的高血压前期的相关性仍不清楚。本研究旨在比较腰围(WC)、腰高比、体圆度指数(BRI)、身体形状指数(ABSI)和锥形指数(CI)等肥胖指数与中国人群高血压前期的相关性。我们从中国广东省的一项人群筛查项目中招募了 61475 名参与者。采用多因素 logistic 回归分析来检测 6 种肥胖指数与高血压前期的相关性。采用受试者工作特征曲线(ROC)分析来评估肥胖指数预测高血压前期的价值。根据血压(BP)水平将个体分为两类:血压正常(<120/80mmHg)和高血压前期(120-139/80-89mmHg)。共有 33233 人患有高血压前期,患病率为 54.04%,男性占 42%。logistic 回归模型均显示,除 ABSI 外,每个肥胖指数均与高血压前期呈正相关(p<0.05)。与其他任何指数相比,体重指数(BMI)与高血压前期的相关性略高。六个指数的标准化比值比(ORs)分别为 1.392、1.361、1.406、1.039、1.372 和 1.151。与其他肥胖指数相比,WC 预测高血压前期的曲线下面积(AUC)明显更高(AUC:0.619,敏感性:57%,特异性:60.6%)。总之,WC 和 BMI 可能是高血压前期的最佳指标。越来越多的证据支持将避免肥胖作为高血压前期的首选一级预防策略,同时控制其他主要高血压危险因素。