质子治疗局部晚期乳腺癌的潜力：临床和技术考虑。

Department of Radiation Oncology, The Irving Greenberg Family Cancer Centre, Ottawa, ON K2H 8P4, Canada.

Department of Radiation Oncology, The Massachusetts General Hospital, Boston, MA 02114, USA.

Curr Oncol. 2023 Feb 28;30(3):2869-2878. doi: 10.3390/curroncol30030219.

Proton therapy is a promising therapeutic modality with unique physical properties that allow for abrupt dose fall-off distal to the target of interest, thereby sparing nearby organs at risk. A number of studies have identified the utility of proton radiation in mitigating treatment related sequelae for patients with locally advanced breast cancers. Thus, in the following review, we highlight clinical and technical considerations for proton radiotherapy delivery in patients with locally advanced breast cancer.

质子治疗是一种很有前途的治疗方式，具有独特的物理特性，可以在靶区以外的部位迅速降低剂量，从而保护附近的危险器官。许多研究已经证明了质子放射治疗在减轻局部晚期乳腺癌患者治疗相关后遗症方面的作用。因此，在下面的综述中，我们重点介绍了局部晚期乳腺癌患者质子放射治疗的临床和技术考虑因素。