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Discontinuation of Conventional Synthetic Disease-Modifying Antirheumatic Drugs in Patients With Rheumatoid Arthritis and Excellent Disease Control.类风湿关节炎病情得到良好控制的患者停用传统合成改善病情抗风湿药物
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Assessments of the unmet need in the management of patients with rheumatoid arthritis: analyses from the NOR-DMARD registry.评估类风湿关节炎患者管理中未满足的需求：来自 NOR-DMARD 登记处的分析。
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Effect of Concomitant Disease-modifying Antirheumatic Drugs and Methotrexate Administration Route on Biologic Treatment Durability in Rheumatoid Arthritis: OBRI Cohort Results.类风湿关节炎中合并疾病修正抗风湿药物和甲氨蝶呤给药途径对生物治疗持久性的影响：OBRI 队列研究结果。
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Effect of tapered versus stable treatment with tumour necrosis factor inhibitors on disease flares in patients with rheumatoid arthritis in remission: a randomised, open label, non-inferiority trial.肿瘤坏死因子抑制剂锥形与稳定治疗对缓解期类风湿关节炎患者疾病复发的影响：一项随机、开放标签、非劣效性试验。
Ann Rheum Dis. 2023 Nov;82(11):1394-1403. doi: 10.1136/ard-2023-224476. Epub 2023 Aug 22.
2
Incorrect Data in Table.表格中的数据有误。
JAMA. 2023 May 9;329(18):1612. doi: 10.1001/jama.2023.6906.

本文引用的文献

1
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update.EULAR 推荐的类风湿关节炎治疗方案：使用合成和生物疾病修正抗风湿药物：2022 更新版。
Ann Rheum Dis. 2023 Jan;82(1):3-18. doi: 10.1136/ard-2022-223356. Epub 2022 Nov 10.
2
Treatment Strategies for Patients With Immune-Mediated Inflammatory Diseases.免疫介导性炎症疾病患者的治疗策略
JAMA. 2021 May 4;325(17):1726-1728. doi: 10.1001/jama.2021.2740.
3
Effect of Half-Dose vs Stable-Dose Conventional Synthetic Disease-Modifying Antirheumatic Drugs on Disease Flares in Patients With Rheumatoid Arthritis in Remission: The ARCTIC REWIND Randomized Clinical Trial.半量与稳定剂量传统合成改善病情抗风湿药物对缓解期类风湿关节炎患者疾病复发的影响：ARCTIC REWIND随机临床试验
JAMA. 2021 May 4;325(17):1755-1764. doi: 10.1001/jama.2021.4542.
4
DMARD-free remission as novel treatment target in rheumatoid arthritis: A systematic literature review of achievability and sustainability.无 DMARD 缓解作为类风湿关节炎的新型治疗目标：实现和可持续性的系统文献回顾。
RMD Open. 2020 May;6(1). doi: 10.1136/rmdopen-2020-001220.
5
Relapse rates in patients with rheumatoid arthritis in stable remission tapering or stopping antirheumatic therapy: interim results from the prospective randomised controlled RETRO study.稳定缓解的类风湿关节炎患者在减少或停止抗风湿治疗时的复发率：前瞻性随机对照 RETRO 研究的中期结果。
Ann Rheum Dis. 2016 Jan;75(1):45-51. doi: 10.1136/annrheumdis-2014-206439. Epub 2015 Feb 6.

Discontinuation of Conventional Synthetic Disease-Modifying Antirheumatic Drugs in Patients With Rheumatoid Arthritis and Excellent Disease Control.

作者信息

Lillegraven Siri, Paulshus Sundlisæter Nina, Aga Anna-Birgitte, Sexton Joseph, Solomon Daniel H, van der Heijde Désirée, Haavardsholm Espen A

机构信息

Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.

Division of Rheumatology, Brigham and Women's Hospital, Boston, Massachusetts.

出版信息

JAMA. 2023 Mar 28;329(12):1024-1026. doi: 10.1001/jama.2023.0492.

DOI:10.1001/jama.2023.0492
PMID:36976288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10051094/
Abstract
摘要