Jakovljević Ivana, Smoljo Iva, Sever Štrukil Zdravka, Pehnec Gordana
Environmental Hygiene Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Toxics. 2023 Feb 27;11(3):228. doi: 10.3390/toxics11030228.
This paper present seasonal variation in the equivalent concentration (BaP) of PAHs in order to assess the potential cancer risk for two different groups of residents via ingestion, dermal contact and inhalation pathways. The possible ecological risk caused by PAH atmospheric deposition based on risk quotient was also estimated. A bulk (total, wet and dry) deposition and PM particle fraction (particles with an equivalent aerodynamic diameter < 10 µm) were collected from June 2020 to May 2021 at an urban residential location in the northern part of Zagreb, Croatia. The monthly average of total equivalent BaP mass concentrations of PM varied from 0.057 ng m in July to 3.656 ng m in December; the annul ∑BaP average was 1.348 ng m. In bulk deposition, ∑BaP mass concentrations varied from 1.94 to 57.60 ng L. In both investigated media, BaP had the highest contribution in carcinogenic activity. For PM media, dermal absorption implied the greatest potential cancer risk, followed by ingestion and inhalation. For bulk media, a moderate ecological risk for BaA, BbF and BaP was observed according to the risk quotient approach.
本文呈现了多环芳烃（PAHs）等效浓度（苯并[a]芘）的季节变化，以便通过摄入、皮肤接触和吸入途径评估两组不同居民的潜在癌症风险。还基于风险商数估算了PAH大气沉降可能造成的生态风险。于2020年6月至2021年5月在克罗地亚萨格勒布北部的一个城市居民区收集了大量（总、湿和干）沉降物以及PM颗粒部分（等效空气动力学直径<10 µm的颗粒）。PM中总等效苯并[a]芘质量浓度的月平均值从7月的0.057 ng/m变化到12月的3.656 ng/m；年度∑苯并[a]芘平均值为1.348 ng/m。在大量沉降物中，∑苯并[a]芘质量浓度从1.94到57.60 ng/L不等。在两种被调查介质中，苯并[a]芘在致癌活性方面贡献最大。对于PM介质，皮肤吸收意味着最大的潜在癌症风险，其次是摄入和吸入。对于大量沉降物介质，根据风险商数方法，观察到苯并[a]蒽、苯并[b]荧蒽和苯并[a]芘存在中等生态风险。
