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中国肥胖女性有症状盆腔器官脱垂的流行病学研究:一项基于中国人群的研究。

An epidemiologic study on symptomatic pelvic organ prolapse in obese Chinese women: a population-based study in China.

作者信息

Li Zhiyi, Xu Tao, Li Zhaoai, Gong Jian, Liu Qing, Wang Yulin, Wang Juntao, Xia Zhijun, Zhu Lan

机构信息

Department of Gynecology and Obstetrics, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People's Republic of China,

Department of Epidemiology and Statistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing, People's Republic of China.

出版信息

Diabetes Metab Syndr Obes. 2018 Nov 16;11:761-766. doi: 10.2147/DMSO.S184451. eCollection 2018.

Abstract

BACKGROUND

The aim of this study was to investigate the prevalence and risk factors of symptomatic pelvic organ prolapse in obese Chinese women.

SUBJECTS AND METHODS

We performed a secondary analysis of 3,105 obese women from an observational cross-sectional study conducted between February 2014 and March 2016 in Mainland China. The obesity standard in our study was the Chinese standard (body mass index ≥28). All the subjects were asked to complete a questionnaire which included age, job, parity, and so on. Symptomatic pelvic organ prolapse (POP) was characterized as being symptomatic and at stage II or higher. Multivariable logistic regression was used to assess the factors associated with symptomatic POP.

RESULTS

The prevalence of symptomatic POP was 15.84% in obese Chinese women, and there was a consistent increasing trend in the prevalence of POP with increasing age, ranging from 4.78% in women between 20 and 29 years of age to 28.21% in women aged 70 years or older (<0.0001). Multivariate analysis shows that the independent risk factors were age, chronic cough (>3 weeks), and gynecological abnormalities. In addition, multiparity was not associated with symptomatic POP in multivariable analysis.

CONCLUSION

Symptomatic POP affects nearly 16% of obese women in People's Republic of China. The prevalence of symptomatic POP increases significantly with age.

摘要

背景

本研究旨在调查中国肥胖女性中症状性盆腔器官脱垂的患病率及危险因素。

对象与方法

我们对2014年2月至2016年3月在中国内地进行的一项观察性横断面研究中的3105名肥胖女性进行了二次分析。我们研究中的肥胖标准为中国标准(体重指数≥28)。所有受试者均被要求填写一份问卷,内容包括年龄、职业、产次等。症状性盆腔器官脱垂(POP)的定义为有症状且处于II期或更高分期。采用多变量逻辑回归分析来评估与症状性POP相关的因素。

结果

中国肥胖女性中症状性POP的患病率为15.84%,且POP的患病率随年龄增长呈持续上升趋势,20至29岁女性中的患病率为4.78%,70岁及以上女性中的患病率为28.21%(<0.0001)。多变量分析显示,独立危险因素为年龄、慢性咳嗽(>3周)和妇科异常。此外,在多变量分析中,多产与症状性POP无关。

结论

在中国,症状性POP影响近16%的肥胖女性。症状性POP的患病率随年龄显著增加。

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