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以及皮肤:抗氧化活性及在皮肤病中的可能治疗作用

and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases.

作者信息

Li Pomi Federica, Papa Vincenzo, Borgia Francesco, Vaccaro Mario, Allegra Alessandro, Cicero Nicola, Gangemi Sebastiano

机构信息

Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, 98125 Messina, Italy.

Department of Clinical and Experimental Medicine, School and Operative Unit of Allergy and Clinical Immunology, University of Messina, 98125 Messina, Italy.

出版信息

Antioxidants (Basel). 2023 Mar 9;12(3):680. doi: 10.3390/antiox12030680.

Abstract

The rosemary plant, Rosmarinus officinalis L., one of the main members of the Lamiaceae family, is currently one of the most promising herbal medicines due to its pharmaceutical properties. This research aimed to evaluate the antioxidant role of Rosmarinus officinalis and its bioactive compounds on the skin, with a focus on the newly emerging molecular mechanisms involved, providing extensive scientific evidence of its anti-inflammatory, antimicrobial, wound-healing and anticancer activity in dermatological practice. The search was conducted on articles concerning in vitro and in vivo studies in both animals and humans. The results obtained confirm the antioxidant role of R. officinalis. This assumption derives the possibility of using R. officinalis or its bioactive elements for the treatment of inflammatory and infectious skin pathologies. However, although the use of rosemary in the treatment of skin diseases represents a fascinating line of research, future perspectives still require large and controlled clinical trials in order to definitively elucidate the real impact of this plant and its components in clinical practice.

摘要

迷迭香植物,即迷迭香叶,是唇形科的主要成员之一,由于其药用特性,目前是最有前景的草药之一。本研究旨在评估迷迭香及其生物活性化合物对皮肤的抗氧化作用,重点关注新出现的相关分子机制,为其在皮肤科实践中的抗炎、抗菌、伤口愈合和抗癌活性提供广泛的科学证据。检索了有关动物和人类体外及体内研究的文章。获得的结果证实了迷迭香的抗氧化作用。这一假设使得使用迷迭香或其生物活性成分治疗炎症性和感染性皮肤疾病成为可能。然而,尽管迷迭香在治疗皮肤疾病方面是一个引人入胜的研究方向,但未来仍需要大规模的对照临床试验,以明确阐明这种植物及其成分在临床实践中的实际影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a73b/10045493/94da99ffa725/antioxidants-12-00680-g001.jpg

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