Mandić Lucija, Matković Marija, Baranović Goran, Šegota Suzana
Ruđer Bošković Institute, Division of Physical Chemistry, 10000 Zagreb, Croatia.
Ruđer Bošković Institute, Division of Organic Chemistry and Biochemistry, 10000 Zagreb, Croatia.
Antioxidants (Basel). 2023 Mar 16;12(3):732. doi: 10.3390/antiox12030732.
The actual cumulative mass of released quercetin from nanoparticles within the dialysis membrane was determined under the influence of external stationary and alternating magnetic fields. We have shown that the control of the release kinetics of quercetin from MNPs, i.e., the distribution of quercetin between the nanoparticles and the suspension within the membrane, can be tuned by the simple combination of stationary and alternating magnetic fields. Under non-sink conditions, the proportion of quercetin in the suspension inside the membrane is increased toward the nanoparticles, resulting in the increased release of quercetin. The results obtained could be applied to the release of insoluble flavonoids in aqueous suspensions in general.
在外部静态磁场和交变磁场的影响下，测定了透析膜内纳米颗粒释放的槲皮素的实际累积质量。我们已经表明，通过静态磁场和交变磁场的简单组合，可以调节槲皮素从磁性纳米颗粒中的释放动力学，即槲皮素在纳米颗粒与膜内悬浮液之间的分布。在非漏槽条件下，膜内悬浮液中槲皮素向纳米颗粒的比例增加，导致槲皮素释放增加。所获得的结果通常可应用于水悬浮液中不溶性黄酮类化合物的释放。
