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近期识别受体在真菌毒素电化学生物传感识别中的研究进展——综述

Recent Advances in Recognition Receptors for Electrochemical Biosensing of Mycotoxins-A Review.

机构信息

Department of Chemistry, Punjab Agricultural University, Ludhiana 141004, India.

Department of Chemistry, Indian Institute of Technology, Ropar 140001, India.

出版信息

Biosensors (Basel). 2023 Mar 17;13(3):391. doi: 10.3390/bios13030391.

Abstract

Mycotoxins are naturally occurring toxic secondary metabolites produced by fungi in cereals and foodstuffs during the stages of cultivation and storage. Electrochemical biosensing has emerged as a rapid, efficient, and economical approach for the detection and quantification of mycotoxins in different sample media. An electrochemical biosensor consists of two main units, a recognition receptor and a signal transducer. Natural or artificial antibodies, aptamers, molecularly imprinted polymers (MIP), peptides, and DNAzymes have been extensively employed as selective recognition receptors for the electrochemical biosensing of mycotoxins. This article affords a detailed discussion of the recent advances and future prospects of various types of recognition receptors exploited in the electrochemical biosensing of mycotoxins.

摘要

真菌在谷物和食品的种植和储存阶段会产生天然存在的有毒次生代谢物,即真菌毒素。电化学生物传感技术是一种快速、高效、经济的方法,可用于检测和定量不同样品介质中的真菌毒素。电化学生物传感器由两个主要单元组成,即识别受体和信号转换器。天然或人工抗体、适体、分子印迹聚合物 (MIP)、肽和 DNA 酶已被广泛用作真菌毒素电化学生物传感的选择性识别受体。本文详细讨论了用于真菌毒素电化学生物传感的各种类型识别受体的最新进展和未来展望。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/910c/10046307/22c3eac05c80/biosensors-13-00391-g001.jpg

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