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六个月内接受口服营养补充剂的学龄前挑食儿童的临床演变:一项前瞻性对照临床试验

Clinical Evolution of Preschool Picky Eater Children Receiving Oral Nutritional Supplementation during Six Months: A Prospective Controlled Clinical Trial.

作者信息

Nogueira-de-Almeida Carlos Alberto, Del Ciampo Luiz Antonio, Martinez Edson Zangiacomi, Contini Andrea Aparecida, Nogueira-de-Almeida Maria Eduarda, Ferraz Ivan Savioli, Epifanio Matias, da Veiga Ued Fabio

机构信息

Medical Department, Federal University of São Carlos, Brazil-DMED UFSCAR Rod. Washington Luiz, km 235, São Carlos 13565-905, Brazil.

Medical School, University of São Paulo, Brazil-FMRP-USPAv, Bandeirantes, 3.900, Ribeirao Preto 14049-900, Brazil.

出版信息

Children (Basel). 2023 Mar 2;10(3):495. doi: 10.3390/children10030495.

DOI:10.3390/children10030495
PMID:36980052
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10047348/
Abstract

OBJECTIVE

To determine if oral nutritional supplementation of picky eater children has a beneficial effect in addition to nutritional guidance on anthropometric parameters, nutrient intake, appetite, physical activity, and health complications.

METHODS

This is a randomized, single-blind, controlled clinical trial that included Brazilian picky eater children aged 24 to 60 months. The individuals were randomized into a control group (CG) ( = 17) and an intervention group (IG) ( = 18), and were followed up in seven meetings for 180 days (baseline plus one meeting every 30 days). The CG received nutritional guidance for food selectivity, while the IG received the same guidance plus oral nutritional supplementation. Anthropometric and nutrient intake assessments were carried out, and appetite, physical activity and health complications were investigated.

RESULTS

In the IG, the z-score of weight and height increased significantly over time ( < 0.05), while the body fat percentage (BFP) and BMI z-score remained unchanged. The percentage of inadequate intake of vitamins D, C and folate reduced in the IG over time compared to the CG ( < 0.05). In the IG, the score assigned by parents to the appetite scale increased over time ( < 0.05). There was no difference between the groups in the scores on the physical activity and global health scales, and in the number of health complications.

CONCLUSIONS

Picky eater children that were supplemented increased their weight not by gaining fat, but due to an increase in stature, as shown by BMI z-score and BFP, that remained unchanged. Furthermore, they showed a decrease in inadequate micronutrient intake during the intervention. An improvement in appetite was also observed over time, attesting to the benefit of supplementation.

摘要

目的

确定对挑食儿童进行口服营养补充,除营养指导外,是否对人体测量参数、营养素摄入、食欲、身体活动和健康并发症有有益影响。

方法

这是一项随机、单盲、对照临床试验,纳入了24至60个月大的巴西挑食儿童。将个体随机分为对照组(CG)(n = 17)和干预组(IG)(n = 18),并在七次会议中随访180天(基线加上每30天一次会议)。CG接受食物选择性的营养指导,而IG接受相同指导并加上口服营养补充。进行了人体测量和营养素摄入评估,并调查了食欲、身体活动和健康并发症。

结果

在IG中,体重和身高的z评分随时间显著增加(P < 0.05),而体脂百分比(BFP)和BMI z评分保持不变。与CG相比,IG中维生素D、C和叶酸摄入不足的百分比随时间降低(P < 0.05)。在IG中,家长给食欲量表的评分随时间增加(P < 0.05)。两组在身体活动和整体健康量表的评分以及健康并发症数量方面没有差异。

结论

补充营养的挑食儿童体重增加并非因脂肪增加,而是由于身高增加,如BMI z评分和BFP所示,它们保持不变。此外,干预期间他们微量营养素摄入不足的情况有所减少。随着时间推移还观察到食欲有所改善,证明了补充营养的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa93/10047348/027ad9f80bb2/children-10-00495-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa93/10047348/7f6a4301410c/children-10-00495-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa93/10047348/cea6cce7e88a/children-10-00495-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa93/10047348/6259ac7578ed/children-10-00495-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa93/10047348/b4530df8142c/children-10-00495-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa93/10047348/027ad9f80bb2/children-10-00495-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa93/10047348/7f6a4301410c/children-10-00495-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa93/10047348/cea6cce7e88a/children-10-00495-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa93/10047348/6259ac7578ed/children-10-00495-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa93/10047348/b4530df8142c/children-10-00495-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa93/10047348/027ad9f80bb2/children-10-00495-g005.jpg

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