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口服营养补充剂可改善有营养不良风险和挑食行为的儿童的生长状况。

Oral Nutritional Supplementation Improves Growth in Children at Malnutrition Risk and with Picky Eating Behaviors.

机构信息

Abbott Nutrition, Research & Development India, 15th Floor, Godrej BKC Plot-C, "G" Block, Bandra Kurla Complex, Bandra East, Mumbai 400051, Maharashtra, India.

Statistical Services, Cognizant Technology Solutions India Private Limited, Manyata Business Park, Nagavara, Bengaluru 560045, Karnataka, India.

出版信息

Nutrients. 2021 Oct 14;13(10):3590. doi: 10.3390/nu13103590.

Abstract

The problem of poor nutrition with impaired growth persists in young children worldwide, including in India, where wasting occurs in 20% of urban children (<5 years). Exacerbating this problem, some children are described by their parent as a picky eater with behaviors such as eating limited food and unwillingness to try new foods. Timely intervention can help prevent nutritional decline and promote growth recovery; oral nutritional supplements (ONS) and dietary counseling (DC) are commonly used. The present study aimed to determine the effects of ONS along with DC on growth in comparison with the effects of DC only. Enrolled children (N = 321) were >24 to ≤48 months old, at malnutrition risk (weight-for-height percentile 3rd to 15th), and described as a picky eater by their parent. Enrollees were randomized to one of the three groups (N = 107 per group): ONS1 + DC; ONS2 + DC; and DC only. From day 1 to day 90, study findings showed significant increases in weight-for-height percentile for ONS1 + DC and for ONS2 + DC interventions, as compared to DC only ( = 0.0086 for both). There was no significant difference between the two ONS groups. Anthropometric measurements (weight and body mass index) also increased significantly over time for the two ONS groups (versus DC only, < 0.05), while ONS1 + DC significantly improved mid-upper-arm circumference ( < 0.05 versus DC only), as well. ONS groups showed a trend toward greater height gain when compared to DC only group, but the differences were not significant within the study interval. For young Indian children with nutritional risk and picky eating behaviors, our findings showed that a 90-day nutritional intervention with either ONS1 or ONS2, along with DC, promoted catch-up growth more effectively than did DC alone.

摘要

全世界包括印度在内的许多地区,幼儿仍然存在营养不良和生长不良的问题,在城市儿童(<5 岁)中,有 20%存在消瘦的情况。由于这个问题的存在,一些儿童被其父母描述为有挑食行为,表现为饮食有限且不愿意尝试新食物。及时干预有助于预防营养状况恶化和促进生长恢复;口服营养补充剂(ONS)和饮食咨询(DC)是常用的干预方法。本研究旨在确定 ONS 联合 DC 对生长的影响,并与仅 DC 的影响进行比较。纳入研究的儿童(N=321)年龄为 24 至 48 个月,有营养不良风险(身高体重百分位数为 3 至 15 百分位),并被其父母描述为挑食。参与者被随机分配到三个组(每组 107 人):ONS1+DC;ONS2+DC;仅 DC。从第 1 天到第 90 天,研究结果显示,与仅 DC 组相比,ONS1+DC 和 ONS2+DC 干预组的身高体重百分位数显著增加(两者均为 =0.0086)。两组 ONS 之间没有显著差异。在 ONS 两组中,体重和体重指数的测量值也随着时间的推移而显著增加(与仅 DC 组相比,均<0.05),而 ONS1+DC 显著改善了中上臂周长(与仅 DC 组相比,<0.05)。与仅 DC 组相比,ONS 组的身高增长趋势更大,但在研究期间差异不显著。对于有营养风险和挑食行为的印度年轻儿童,我们的研究结果表明,ONS1 或 ONS2 联合 DC 的 90 天营养干预比单独使用 DC 更能有效促进追赶生长。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08ce/8538528/b8c4f38f070a/nutrients-13-03590-g001.jpg

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