Uhler Kristin, Tollin Daniel J, Gilley Phillip M
Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz School of Medicine & Children's Hospital Colorado, Aurora, CO 80045, USA.
Department of Physiology and Biophysics, University of Colorado Anschutz School of Medicine, Aurora, CO 80045, USA.
Children (Basel). 2023 Mar 21;10(3):600. doi: 10.3390/children10030600.
Our objective was to examine the effects of hearing aid amplification on auditory detection and discrimination in nfants who were ard of earing (IHH) using a physiological measure of auditory perception. We recorded EEG from 41 sleeping IHH aged 1.04 to 5.62 months while presenting auditory stimuli in a mismatch response paradigm. Responses were recorded during two listening conditions for each participant: aided and unaided. Temporal envelopes of the mismatch response in the EEG alpha band (6-12 Hz) were extracted from the latent, time-frequency transformed data. Aided alpha band responses were greater than unaided responses for the deviant trials but were not different for the standard trials. Responses to the deviant trials were greater than responses to the standard trials for the aided conditions but were not different for the unaided conditions. These results suggest that the alpha band mismatch can be used to examine both detection and discrimination of speech and non-speech sounds in IHH. With further study, the alpha band mismatch could expand and refine our abilities to validate hearing aid fittings at younger ages than current clinical protocols allow.
我们的目标是使用听觉感知的生理测量方法，研究助听器放大对听力减退婴儿（IHH）听觉检测和辨别能力的影响。我们在41名年龄在1.04至5.62个月的睡眠中的IHH婴儿身上记录脑电图（EEG），同时在失配反应范式中呈现听觉刺激。为每位参与者在两种聆听条件下记录反应：佩戴助听器和未佩戴助听器。从潜在的时频变换数据中提取脑电图α波段（6-12赫兹）中失配反应的时间包络。对于偏差试验，佩戴助听器时α波段反应大于未佩戴助听器时的反应，但对于标准试验则无差异。在佩戴助听器条件下，对偏差试验的反应大于对标准试验的反应，但在未佩戴助听器条件下则无差异。这些结果表明，α波段失配可用于检测和辨别IHH婴儿的语音和非语音声音。通过进一步研究，α波段失配可以扩展和完善我们在比当前临床方案允许的更年轻年龄验证助听器适配的能力。
