Christopoulos Panagiotis, Matsas Alkis, Eleftheriades Makarios, Kotsira Georgia, Eleftheriades Anna, Vlahos Nikolaos F
Second Department of Obstetrics and Gynecology, "Aretaieion" Hospital, Faculty of Medicine, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Children (Basel). 2023 Mar 21;10(3):601. doi: 10.3390/children10030601.
Several factors during childhood and adolescence are thought to be associated with the development of proliferative benign breast diseases and breast cancer in adulthood. In order to identify them, the authors conducted an extensive review of the literature up to October 2022, searching for clinical studies, reports, and guidelines in English. A thorough Medline/Pubmed and Google scholar database research was performed, investigating the link between diet, exercise, age of menarche, body mass index, ionizing radiation exposure during childhood and adolescence, and proliferative breast diseases and breast cancer in adulthood. A list of keywords, including breast disorders, adolescence, childhood, and breast cancer was included in our search algorithm. Numerous studies concede that the development of breast disease in adulthood is influenced by various risk factors, whose influence begins during early childhood and adolescence.
儿童期和青春期的几个因素被认为与成年期增生性良性乳腺疾病和乳腺癌的发生有关。为了确定这些因素,作者对截至2022年10月的文献进行了广泛回顾,搜索英文的临床研究、报告和指南。对Medline/Pubmed和谷歌学术数据库进行了全面研究,调查饮食、运动、初潮年龄、体重指数、儿童期和青春期的电离辐射暴露与成年期增生性乳腺疾病和乳腺癌之间的联系。我们的搜索算法中包含了一系列关键词,包括乳腺疾病、青春期、儿童期和乳腺癌。许多研究承认,成年期乳腺疾病的发生受到多种风险因素的影响,这些因素的影响始于儿童早期和青春期。