Faculty of Medicine, Riga Stradiņš University, Dzirciema Street 16, LV 1007 Riga, Latvia.
Department of pharmacology, Riga Stradins University, Dzirciema Street 16, LV 1007 Riga, Latvia.
Int J Environ Res Public Health. 2023 Mar 13;20(6):5061. doi: 10.3390/ijerph20065061.
The global coronavirus pandemic has significantly impacted public health and has been a research subject since its emergence in 2019. The acute phase of the disease leads to pulmonary and non-pulmonary manifestations, which in some individuals may progress to long-lasting symptoms. In this article, we conducted a narrative review of the current literature to summarize current knowledge regarding long COVID syndrome in children, focusing on cognitive symptoms. The review included a search of three databases (PubMed, Embase, and Web of Science) using the key phrases "post COVID-19 cognitive pediatric", "long COVID pediatric", "mental health long COVID children", and "COVID-19 cognitive symptoms". A total of 102 studies were included. The review revealed that the main long-term cognitive symptoms following COVID-19 were memory and concentration deficits, sleep disturbances, and psychiatric states such as anxiety and stress. In addition to the direct physiological effects of a viral infection, there are psychological, behavioral, and social factors contributing to cognitive impairment, which should be addressed regarding the pediatric population. The high prevalence of neurocognitive symptoms in children following COVID-19 emphasizes the importance of understanding the mechanisms of nervous system involvement.
全球冠状病毒大流行对公共卫生造成了重大影响,自 2019 年出现以来一直是研究课题。疾病的急性期导致肺部和非肺部表现,在某些个体中,可能会进展为持久的症状。在本文中,我们对当前文献进行了叙述性综述,以总结目前关于儿童长新冠综合征的知识,重点关注认知症状。综述包括使用关键词“post COVID-19 cognitive pediatric”、“long COVID pediatric”、“mental health long COVID children”和“COVID-19 cognitive symptoms”在三个数据库(PubMed、Embase 和 Web of Science)中进行的搜索。共纳入了 102 项研究。综述结果表明,COVID-19 后主要的长期认知症状包括记忆力和注意力缺陷、睡眠障碍以及焦虑和压力等精神状态。除了病毒感染的直接生理影响外,还有心理、行为和社会因素导致认知障碍,这在儿科人群中应加以解决。儿童 COVID-19 后出现神经认知症状的高患病率强调了了解神经系统受累机制的重要性。