• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

新冠长期症状对儿童和青少年的社会、学业及健康状况的影响:一项观察性、描述性纵向队列研究

Social, Academic, and Health Status Impact of Long COVID on Children and Young People: An Observational, Descriptive, and Longitudinal Cohort Study.

作者信息

Gonzalez-Aumatell Alba, Bovo Maria Victoria, Carreras-Abad Clara, Cuso-Perez Sara, Domènech Marsal Èlia, Coll-Fernández Roser, Goicoechea Calvo Aroia, Giralt-López Maria, Enseñat Cantallops Antonia, Moron-Lopez Sara, Martinez-Picado Javier, Sol Ventura Paula, Rodrigo Carlos, Méndez Hernández Maria

机构信息

Department of Pediatrics, Germans Trias i Pujol University Hospital, 08916 Badalona, Spain.

Department of Pediatrics, Obstetrics and Gynecology, Preventive Medicine and Public Health, Faculty of Medicine, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, Spain.

出版信息

Children (Basel). 2022 Oct 31;9(11):1677. doi: 10.3390/children9111677.

DOI:10.3390/children9111677
PMID:36360405
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9689050/
Abstract

There is a lack of evidence of the health impacts due to long COVID among children and young people (CYP). The objective of this study is to determine the main clinical characteristics of long COVID in CYP and to investigate the academic, social, and health status impacts of long COVID in this population. An observational, descriptive, and longitudinal study on CYP who presented COVID-19 symptoms for more than twelve weeks after SARS-CoV-2 infection was performed between December 2020 and May 2021. Fifty CYP were included, with a median age of 14.1 years, 33 (66%) were female, and 17 (34%) had a relative diagnosed with long COVID. Since the initial infection and up to the first visit, CYP had persisting symptoms for a median of 4.1 months, and for 18 (36%) CYP these symptoms persisted for more than 6 months. Fatigue (100%), neurocognitive disorders (74%), muscular weakness (74%), and headache (72%) were the most reported symptoms. A total of 9 (18%) CYP could not attend school, 17 (34%) had a reduced schedule, 33 (66%) showed a decreased school performance, and 68% had stopped extracurricular activities. This preliminary study shows the impact that long COVID has on the health, academic, and social life of CYP.

摘要

缺乏关于儿童和青少年(CYP)长期新冠健康影响的证据。本研究的目的是确定CYP长期新冠的主要临床特征,并调查长期新冠对该人群学业、社交和健康状况的影响。2020年12月至2021年5月期间,对感染SARS-CoV-2后出现新冠症状超过12周的CYP进行了一项观察性、描述性纵向研究。纳入了50名CYP,中位年龄为14.1岁,33名(66%)为女性,17名(34%)有亲属被诊断为长期新冠。从初次感染到首次就诊,CYP持续症状的中位时间为4.1个月,18名(36%)CYP的这些症状持续超过6个月。最常报告的症状为疲劳(100%)、神经认知障碍(74%)、肌肉无力(74%)和头痛(72%)。共有9名(18%)CYP无法上学,17名(34%)上课时间减少,33名(66%)学业成绩下降,68%停止了课外活动。这项初步研究显示了长期新冠对CYP健康、学业和社会生活的影响。

相似文献

1
Social, Academic, and Health Status Impact of Long COVID on Children and Young People: An Observational, Descriptive, and Longitudinal Cohort Study.新冠长期症状对儿童和青少年的社会、学业及健康状况的影响:一项观察性、描述性纵向队列研究
Children (Basel). 2022 Oct 31;9(11):1677. doi: 10.3390/children9111677.
2
Persistent symptoms are associated with long term effects of COVID-19 among children and young people: Results from a systematic review and meta-analysis of controlled studies.持续性症状与儿童和青少年 COVID-19 的长期影响有关:一项系统评价和对照研究荟萃分析的结果。
PLoS One. 2023 Dec 28;18(12):e0293600. doi: 10.1371/journal.pone.0293600. eCollection 2023.
3
Natural course of health and well-being in non-hospitalised children and young people after testing for SARS-CoV-2: a prospective follow-up study over 12 months.SARS-CoV-2检测后非住院儿童和青少年的健康与幸福自然病程:一项为期12个月的前瞻性随访研究
Lancet Reg Health Eur. 2023 Feb;25:100554. doi: 10.1016/j.lanepe.2022.100554. Epub 2022 Dec 5.
4
Experiences and care needs of children with long COVID: a qualitative study.新冠长期症状患儿的经历与护理需求:一项定性研究
BJGP Open. 2024 Apr 25;8(1). doi: 10.3399/BJGPO.2023.0143. Print 2024 Apr.
5
Long COVID (post-COVID-19 condition) in children: a modified Delphi process.儿童长新冠(新冠后状况):改良德尔菲法。
Arch Dis Child. 2022 Jul;107(7):674-680. doi: 10.1136/archdischild-2021-323624. Epub 2022 Apr 1.
6
COVID-19 deaths in children and young people in England, March 2020 to December 2021: An active prospective national surveillance study.2020 年 3 月至 2021 年 12 月英格兰儿童和青少年的 COVID-19 死亡病例:一项主动的全国前瞻性监测研究。
PLoS Med. 2022 Nov 8;19(11):e1004118. doi: 10.1371/journal.pmed.1004118. eCollection 2022 Nov.
7
Health outcomes in people 2 years after surviving hospitalisation with COVID-19: a longitudinal cohort study.COVID-19 住院幸存者 2 年后的健康结局:一项纵向队列研究。
Lancet Respir Med. 2022 Sep;10(9):863-876. doi: 10.1016/S2213-2600(22)00126-6. Epub 2022 May 11.
8
Interventions to improve the mental health of children and young people with long-term physical conditions: linked evidence syntheses.改善患有长期身体状况的儿童和青少年心理健康的干预措施:综合证据的关联分析。
Health Technol Assess. 2019 May;23(22):1-164. doi: 10.3310/hta23220.
9
COVID-19 symptom surveillance in immunocompromised children and young people in the UK: a prospective observational cohort study.英国免疫功能低下儿童和青少年的 COVID-19 症状监测:一项前瞻性观察队列研究。
BMJ Open. 2021 Mar 17;11(3):e044899. doi: 10.1136/bmjopen-2020-044899.
10
Symptom patterns and life with post-acute COVID-19 in children aged 8-17 years: a mixed-methods study protocol.8至17岁儿童急性后新冠病毒感染的症状模式与生活:一项混合方法研究方案
BJGP Open. 2023 Jun 27;7(2). doi: 10.3399/BJGPO.2022.0149. Print 2023 Jun.

引用本文的文献

1
"A PhD is just going to somehow break you": A qualitative study exploring the role of peer support for doctoral students.“博士学位会在某种程度上把你压垮”:一项探索同伴支持对博士生作用的定性研究。
PLoS One. 2025 Jun 9;20(6):e0325726. doi: 10.1371/journal.pone.0325726. eCollection 2025.
2
Neuropsychiatric Manifestations of Long COVID-19: A Narrative Review of Clinical Aspects and Therapeutic Approaches.长新冠的神经精神表现:临床方面与治疗方法的叙述性综述
Life (Basel). 2025 Mar 11;15(3):439. doi: 10.3390/life15030439.
3
A systematic review of post COVID-19 condition in children and adolescents: Gap in evidence from low-and -middle-income countries and the impact of SARS-COV-2 variants.

本文引用的文献

1
Prevalence and Characteristics of Persistent Symptoms in Children During the COVID-19 Pandemic: Evidence From a Household Cohort Study in England and Wales.新冠疫情期间儿童持续症状的患病率及特征:来自英格兰和威尔士一项家庭队列研究的证据
Pediatr Infect Dis J. 2022 Dec 1;41(12):979-984. doi: 10.1097/INF.0000000000003715. Epub 2022 Oct 21.
2
Post-COVID-19-associated morbidity in children, adolescents, and adults: A matched cohort study including more than 157,000 individuals with COVID-19 in Germany.儿童、青少年和成年人的新冠后并发症:一项匹配队列研究,纳入了德国超过 157000 例新冠患者。
PLoS Med. 2022 Nov 10;19(11):e1004122. doi: 10.1371/journal.pmed.1004122. eCollection 2022 Nov.
3
儿童和青少年新冠后状况的系统评价:低收入和中等收入国家的证据差距以及新冠病毒变异株的影响
PLoS One. 2025 Mar 3;20(3):e0315815. doi: 10.1371/journal.pone.0315815. eCollection 2025.
4
Chronic Symptomatology Among Infants, Children, and Adolescents Within 12 Months After SARS-CoV-2 Infection.新冠病毒感染后12个月内婴幼儿、儿童及青少年的慢性症状学
Glob Pediatr Health. 2024 Oct 16;11:2333794X241287096. doi: 10.1177/2333794X241287096. eCollection 2024.
5
Evaluating the risk of sleep disorders in subjects with a prior COVID-19 infection.评估既往 COVID-19 感染患者睡眠障碍的风险。
PLoS One. 2024 Oct 17;19(10):e0311929. doi: 10.1371/journal.pone.0311929. eCollection 2024.
6
Salivary biomarkers as pioneering indicators for diagnosis and severity stratification of pediatric long COVID.唾液生物标志物可作为儿科长新冠诊断和严重程度分层的开创性指标。
Front Cell Infect Microbiol. 2024 May 31;14:1396263. doi: 10.3389/fcimb.2024.1396263. eCollection 2024.
7
The importance of post-COVID condition phenotypes characterization to decipher the mechanisms underlying this post-viral syndrome.新冠后状况的表型特征对于解读这种病毒后综合征背后的机制的重要性。
World J Pediatr. 2024 Jun;20(6):633-634. doi: 10.1007/s12519-024-00812-3.
8
Neuropsychological functioning of pediatric patients with long COVID.儿童长新冠患者的神经心理学功能。
Clin Neuropsychol. 2024 Nov;38(8):1855-1872. doi: 10.1080/13854046.2024.2344455. Epub 2024 Apr 25.
9
Long COVID and post-acute sequelae of SARS-CoV-2 pathogenesis and treatment: A Keystone Symposia report.新冠长期症状与SARS-CoV-2发病机制及治疗的急性后遗症:基石研讨会报告
Ann N Y Acad Sci. 2024 May;1535(1):31-41. doi: 10.1111/nyas.15132. Epub 2024 Apr 9.
10
How does post COVID differ from other post-viral conditions in childhood and adolescence (0-20 years old)? A systematic review.新冠康复后在儿童和青少年(0至20岁)中与其他病毒感染后状况有何不同?一项系统综述。
EClinicalMedicine. 2024 Feb 2;68:102436. doi: 10.1016/j.eclinm.2024.102436. eCollection 2024 Feb.
Case report: Persistence of residual antigen and RNA of the SARS-CoV-2 virus in tissues of two patients with long COVID.
病例报告:两名长新冠患者组织中持续存在 SARS-CoV-2 病毒的残余抗原和 RNA。
Front Immunol. 2022 Sep 5;13:939989. doi: 10.3389/fimmu.2022.939989. eCollection 2022.
4
Prevalence and risk factors of post-COVID-19 condition in adults and children at 6 and 12 months after hospital discharge: a prospective, cohort study in Moscow (StopCOVID).COVID-19 后成年人和儿童在出院后 6 个月和 12 个月的患病率和危险因素:莫斯科(StopCOVID)的一项前瞻性队列研究。
BMC Med. 2022 Jul 6;20(1):244. doi: 10.1186/s12916-022-02448-4.
5
Post COVID-19 Condition in Children and Adolescents: An Emerging Problem.儿童和青少年的新冠后状况:一个新出现的问题。
Front Pediatr. 2022 May 11;10:894204. doi: 10.3389/fped.2022.894204. eCollection 2022.
6
Lung Abnormalities Detected with Hyperpolarized Xe MRI in Patients with Long COVID.长新冠患者的超极化氙 MRI 检测到肺部异常。
Radiology. 2022 Dec;305(3):709-717. doi: 10.1148/radiol.220069. Epub 2022 May 24.
7
Clinical characteristics, activity levels and mental health problems in children with long coronavirus disease: a survey of 510 children.儿童长新冠疾病的临床特征、活动水平和心理健康问题:对 510 名儿童的调查。
Future Microbiol. 2022 May;17(8):577-588. doi: 10.2217/fmb-2021-0285. Epub 2022 Apr 1.
8
Multiple early factors anticipate post-acute COVID-19 sequelae.多种早期因素预示着急性新冠病毒感染后会出现长期新冠症状。
Cell. 2022 Mar 3;185(5):881-895.e20. doi: 10.1016/j.cell.2022.01.014. Epub 2022 Jan 25.
9
Comparison of mental health outcomes in seropositive and seronegative adolescents during the COVID19 pandemic.比较 COVID19 大流行期间血清阳性和血清阴性青少年的心理健康结果。
Sci Rep. 2022 Feb 10;12(1):2246. doi: 10.1038/s41598-022-06166-y.
10
Physical and mental health 3 months after SARS-CoV-2 infection (long COVID) among adolescents in England (CLoCk): a national matched cohort study.SARS-CoV-2 感染(长新冠)后 3 个月青少年的身心健康(CLoCk):一项全国匹配队列研究。
Lancet Child Adolesc Health. 2022 Apr;6(4):230-239. doi: 10.1016/S2352-4642(22)00022-0. Epub 2022 Feb 8.