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骨科领域中的人工智能应用:利用预测分析和机器学习预测关节镜下肩袖手术结果

Approaching Artificial Intelligence in Orthopaedics: Predictive Analytics and Machine Learning to Prognosticate Arthroscopic Rotator Cuff Surgical Outcomes.

作者信息

Potty Anish G, Potty Ajish S R, Maffulli Nicola, Blumenschein Lucas A, Ganta Deepak, Mistovich R Justin, Fuentes Mario, Denard Patrick J, Sethi Paul M, Shah Anup A, Gupta Ashim

机构信息

South Texas Orthopedic Research Institute (STORI Inc.), Laredo, TX 78045, USA.

The Institute of Musculoskeletal Excellence (TIME Orthopaedics), Laredo, TX 78041, USA.

出版信息

J Clin Med. 2023 Mar 19;12(6):2369. doi: 10.3390/jcm12062369.

DOI:10.3390/jcm12062369
PMID:36983368
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10056706/
Abstract

Machine learning (ML) has not yet been used to identify factors predictive for post-operative functional outcomes following arthroscopic rotator cuff repair (ARCR). We propose a novel algorithm to predict ARCR outcomes using machine learning. This is a retrospective cohort study from a prospectively collected database. Data were collected from the Surgical Outcome System Global Registry (Arthrex, Naples, FL, USA). Pre-operative and 3-month, 6-month, and 12-month post-operative American Shoulder and Elbow Surgeons (ASES) scores were collected and used to develop a ML model. Pre-operative factors including demography, comorbidities, cuff tear, tissue quality, and fixation implants were fed to the ML model. The algorithm then produced an expected post-operative ASES score for each patient. The ML-produced scores were compared to actual scores using standard test-train machine learning principles. Overall, 631 patients who underwent shoulder arthroscopy from January 2011 to March 2020 met inclusion criteria for final analysis. A substantial number of the test dataset predictions using the XGBoost algorithm were within the minimal clinically important difference (MCID) and substantial clinical benefit (SCB) thresholds: 67% of the 12-month post-operative predictions were within MCID, while 84% were within SCB. Pre-operative ASES score, pre-operative pain score, body mass index (BMI), age, and tendon quality were the most important features in predicting patient recovery as identified using Shapley additive explanations (SHAP). In conclusion, the proposed novel machine learning algorithm can use pre-operative factors to predict post-operative ASES scores accurately. This can further supplement pre-operative counselling, planning, and resource allocation. Level of Evidence: III.

摘要

机器学习(ML)尚未用于识别关节镜下肩袖修复术(ARCR)后预测术后功能结局的因素。我们提出了一种使用机器学习预测ARCR结局的新算法。这是一项基于前瞻性收集数据库的回顾性队列研究。数据收集自外科手术结局系统全球注册中心(美国佛罗里达州那不勒斯市的Arthrex公司)。收集术前以及术后3个月、6个月和12个月的美国肩肘外科医师学会(ASES)评分,并用于建立ML模型。将包括人口统计学、合并症、肩袖撕裂、组织质量和固定植入物等术前因素输入ML模型。然后,该算法为每位患者生成预期的术后ASES评分。使用标准的测试-训练机器学习原理,将ML生成的评分与实际评分进行比较。总体而言,2011年1月至2020年3月期间接受肩关节镜检查的631例患者符合最终分析的纳入标准。使用XGBoost算法对大量测试数据集的预测结果在最小临床重要差异(MCID)和显著临床获益(SCB)阈值范围内:术后12个月预测结果的67%在MCID范围内,而84%在SCB范围内。使用Shapley加性解释(SHAP)确定,术前ASES评分、术前疼痛评分、体重指数(BMI)、年龄和肌腱质量是预测患者恢复情况的最重要特征。总之,所提出的新型机器学习算法可以利用术前因素准确预测术后ASES评分。这可以进一步补充术前咨询、规划和资源分配。证据级别:III级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c0a/10056706/e00be370ba15/jcm-12-02369-g007.jpg
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