Department of Urology, China Medical University Hospital, Taichung 404332, Taiwan.
School of Medicine, College of Medicine, China Medical University, Taichung 404333, Taiwan.
Medicina (Kaunas). 2023 Feb 24;59(3):454. doi: 10.3390/medicina59030454.
Chondrosarcoma is a rare type of cancer that can affect the upper urinary tract. Because of its rarity, the clinical presentation of chondrosarcoma can be similar to other urinary tract conditions, such as renal colic, hematuria, and urothelial carcinoma. The primary treatment for chondrosarcoma is the surgical removal of the tumor, and radiation or chemotherapy may be used for advanced cases. However, because of the limited number of patients with this condition, there are no established guidelines for chemotherapy, and the outcomes are unclear. In this case, we present a 71-year-old female patient who was diagnosed with ureteral chondrosarcoma. She presented with abdominal pain and hydronephrosis, and a tumor was found beneath a small stone. The patient underwent nephroureterectomy and received oral fluorouracil chemotherapy due to the advanced stage of the disease. Fortunately, the patient survived, and at the 7 months post-operative follow-up there was no evidence of recurrence. In conclusion, the chondrosarcoma of the upper urinary tract is a rare condition that can be difficult to diagnose due to its similarity to other urinary tract conditions. Treatment typically involves the surgical removal of the tumor, with radiation or chemotherapy reserved for advanced cases. However, because of the limited number of patients, there are no established guidelines for chemotherapy, and the outcomes of treatment are unclear.
软骨肉瘤是一种罕见的癌症，可影响上尿路。由于其罕见性，软骨肉瘤的临床表现可能与其他尿路疾病相似，如肾绞痛、血尿和尿路上皮癌。软骨肉瘤的主要治疗方法是手术切除肿瘤，对于晚期病例可能会使用放射或化疗。然而，由于此类疾病的患者数量有限，目前还没有确立化疗的指南，其治疗效果也不明确。在此，我们报告了一例 71 岁女性患者，被诊断为输尿管软骨肉瘤。她因腹痛和肾积水就诊，在一小结石下方发现一个肿瘤。由于疾病处于晚期，患者接受了肾输尿管切除术，并接受了口服氟尿嘧啶化疗。幸运的是，患者存活下来，在术后 7 个月的随访中没有复发的证据。总之，上尿路软骨肉瘤是一种罕见的疾病，由于其与其他尿路疾病相似，可能难以诊断。治疗通常涉及手术切除肿瘤，对于晚期病例保留放射或化疗。然而，由于患者数量有限，目前还没有确立化疗的指南，其治疗效果也不明确。
