Department of Pharmaceutical Technology, Faculty of Pharmacy, Istanbul Health and Technology University, Istanbul 34015, Turkey.
Department of Pharmacology, Faculty of Pharmacy, Istanbul Health and Technology University, Istanbul 34015, Turkey.
Medicina (Kaunas). 2023 Feb 27;59(3):467. doi: 10.3390/medicina59030467.
: Phytotherapeutically, various herbal remedies, such as St. John's wort oil, have been introduced as wound care options. Recently, Neem oil has been considered a herbal option for the management of superficial wounds. Wound care is a complex process that involves several factors including the patient, caregiver, and medications. Herbal combinations could be an alternative to the chemical counterparts in the wound care area. This report includes an investigation of the possible supportive impacts of the St. John's wort and Neem oil containing ointment (W Cura G Plus ) in the management of pressure ulcers (PUs) in three intensive care unit (ICU) patients. : The ointment was administered to individuals once daily for 42 consecutive days. The status of individuals was macroscopically monitored by measuring the PU area and histopathological assessment of the tissue sections taken on the first and last days of wound treatment. : The outcomes of the macroscopic and histopathological techniques exhibited that St. John's wort and Neem oil containing ointment provided a remarkable supportive impact on the patients that suffered from PUs in the ICUs. : The combination of St. John's wort and Neem oil could be suggested as an efficient active phytoconstituent for the management of PUs. The herbal ointments may be suggested as an alternative for the patients that have PUs in the ICUs.
: 在植物疗法中，已经引入了各种草药疗法，如贯叶金丝桃油，作为伤口护理的选择。最近，印度楝油已被认为是管理浅表伤口的草药选择。伤口护理是一个复杂的过程，涉及多个因素，包括患者、护理人员和药物。草药组合可能是伤口护理领域化学药物的替代品。本报告包括对含有贯叶金丝桃和印度楝油的软膏（W Cura G Plus）在管理 3 名重症监护病房（ICU）患者的压疮（PU）方面的可能支持作用的调查。: 软膏每天给药一次，连续 42 天。通过测量 PU 面积和在伤口治疗的第一天和最后一天获取的组织切片的组织病理学评估，对个体的状况进行宏观监测。: 宏观和组织病理学技术的结果表明，含有贯叶金丝桃和印度楝油的软膏对 ICU 中患有 PU 的患者提供了显著的支持作用。: 贯叶金丝桃和印度楝油的组合可以被建议作为管理 PU 的有效活性植物成分。草药软膏可被建议作为 ICU 中患有 PU 的患者的替代药物。
