Goldman C D, Kodner I J, Fry R D, MacDermott R P
Dis Colon Rectum. 1986 May;29(5):317-21. doi: 10.1007/BF02554120.
Fifteen black patients with Crohn's disease were seen during a ten-year period (1975-1985). They represented 11 percent of our experience with Crohn's disease during that time. These patients had an earlier age of onset of Crohn's symptoms than our white patients, and correct diagnosis was delayed for an average of four years. All 15 patients required abdominal surgery, and seven (47 percent) suffered recurrences necessitating additional abdominal operations. The five-year actuarial estimate of probability of reoperation was 77 percent. Extraintestinal manifestations were present in all patients, and six (40 percent) had multiple manifestations. These disease manifestations are more severe than those noted in series that studied predominantly caucasian Crohn's populations, and suggest that Crohn's disease in the black patient is a distinctly aggressive form.
在10年期间（1975年至1985年）共诊治了15例患有克罗恩病的黑人患者。他们占我们在那段时间诊治克罗恩病患者总数的11%。这些患者出现克罗恩病症状的年龄比白人患者更早，且正确诊断平均延迟了4年。所有15例患者均需接受腹部手术，其中7例（47%）复发，需要再次进行腹部手术。再次手术概率的5年精算估计为77%。所有患者均有肠外表现，6例（40%）有多种表现。这些疾病表现比主要研究白种人克罗恩病患者的系列研究中所记录的更为严重，提示黑人患者的克罗恩病是一种明显具有侵袭性的类型。
