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义齿性口炎:一种跨学科的临床综述。

Denture stomatitis-An interdisciplinary clinical review.

机构信息

Dublin Dental University Hospital, Trinity College Dublin, Dublin, Ireland.

Private Practice, Dublin, Ireland.

出版信息

J Prosthodont. 2023 Aug;32(7):560-570. doi: 10.1111/jopr.13687. Epub 2023 Apr 18.

Abstract

PURPOSE

An interdisciplinary clinical review on denture stomatitis formulated by experts from prosthodontics, oral medicine, and oral microbiology is presented. The review outlines the etiopathogenesis, clinical features, and management strategies of denture stomatitis from an interdisciplinary perspective.

MATERIALS AND METHODS

English-language articles relating to the definition, incidence, gender distribution, geographical distribution, etiology, pathogenesis, symptoms, signs, treatment, and prognosis of denture stomatitis were retrieved via electronic literature search. Relevant articles were summarized for this manuscript with a view toward providing pragmatic information.

RESULTS

Denture stomatitis represents a very common, multifactorial infectious, inflammatory, and hyperplastic condition which is primarily caused by poor oral hygiene, poor denture hygiene, and full-time; mainly night-time denture wear, bringing about the emergence of advanced Candida-containing polymicrobial biofilms in close proximity to the host's mucosal tissues. Denture stomatitis shares clinically relevant associations with dental caries, periodontitis, median rhomboid glossitis, angular cheilitis, aspirational pneumonia, and associated mortality.

CONCLUSIONS

Effective, long-term treatment of denture stomatitis relies upon sustained patient-driven behavioral change which should focus on daily prosthesis-level cleaning and disinfection, removal of dentures at night, every night, engagement with professional denture maintenance, and when required, denture replacement. Antifungal medications offer limited benefits outside of short-term use due to the emergence of antifungal resistance. For frail, older, medically compromised, and nursing home populations, treatment of denture stomatitis lowers the risk of aspirational pneumonia and associated mortality.

摘要

目的

本文呈现了由口腔修复学、口腔医学和口腔微生物学专家制定的义齿性口炎的跨学科临床综述。该综述从跨学科角度概述了义齿性口炎的病因发病机制、临床特征和治疗策略。

材料和方法

通过电子文献检索,检索了与义齿性口炎的定义、发病率、性别分布、地理分布、病因、发病机制、症状、体征、治疗和预后相关的英文文章。本文对相关文章进行了总结,以期提供实用信息。

结果

义齿性口炎是一种非常常见的多因素感染性、炎症性和增生性疾病,主要由口腔卫生不良、义齿卫生不良和全日、主要是夜间戴义齿引起,导致宿主黏膜组织附近出现先进的含念珠菌的多微生物生物膜。义齿性口炎与龋齿、牙周炎、菱形舌炎、口角炎、吸入性肺炎和相关死亡率有临床相关关联。

结论

义齿性口炎的有效长期治疗依赖于患者驱动的行为持续改变,应重点关注日常义齿水平清洁和消毒、夜间每晚取下义齿、专业义齿维护以及在需要时更换义齿。由于出现抗真菌耐药性,抗真菌药物在短期使用之外的获益有限。对于体弱、年老、合并医学疾病和疗养院人群,治疗义齿性口炎可降低吸入性肺炎和相关死亡率的风险。

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