Sommer H, Schmidt M, Gruber K D
Dtsch Med Wochenschr. 1986 May 23;111(21):812-5. doi: 10.1055/s-2008-1068536.
Lung functions were tested (by whole-body plethysmography, pneumotachography, CO diffusion, blood-gas analysis) in 54 patients with Crohn's disease, 21 with ulcerative colitis and 43 healthy subjects. Abnormalities of pulmonary function were found in 38% of those with ulcerative colitis and 54% with Crohn's disease, significantly more often (p less than 0.005) than in the healthy controls (7%). Obstructive disorders were more frequent in patients with ulcerative colitis than Crohn's disease (p less than 0.01), the latter having mainly restrictive and diffusion abnormalities. The abnormal results were unrelated to previous drug treatment as well as duration, activity and site of the disease. The cause of the respiratory abnormalities remain unexplained, but they may be extra-intestinal manifestations of ulcerative colitis and Crohn's disease.
对54例克罗恩病患者、21例溃疡性结肠炎患者和43名健康受试者进行了肺功能测试（通过全身体积描记法、流速仪、一氧化碳弥散、血气分析）。溃疡性结肠炎患者中38%以及克罗恩病患者中54%存在肺功能异常，明显高于健康对照组（7%）（p<0.005）。溃疡性结肠炎患者阻塞性疾病比克罗恩病患者更常见（p<0.01），后者主要存在限制性和弥散性异常。异常结果与既往药物治疗以及疾病的病程、活动度和部位无关。呼吸异常的原因尚不清楚，但可能是溃疡性结肠炎和克罗恩病的肠外表现。
