Iwama T, Higuchi T, Imajo M, Akagawa S, Matsubara O, Mishima Y
Research Center for Polyposis and Intestinal Diseases, Tokyo Medical and Dental University, Japan.
Jpn J Surg. 1991 Jul;21(4):454-7. doi: 10.1007/BF02470975.
A case of Crohn's enterocolitis associated with diffuse tracheo-bronchitis is presented herein. Although respiratory tract involvement in Crohn's disease is extremely rare, our review of the world literature revealed several common clinical pathologic features. These features include a productive cough with chest X-ray films which are normal except for some peripheral involvement. Bronchoscopy, however, shows diffuse inflammation of the trachea and bronchi with widely scattered whitish lesions while biopsy reveals a granulomatous infiltration of inflammatory cells. This tracheobronchitis typically responds well to treatment with prednisone.
本文报告一例克罗恩氏小肠结肠炎合并弥漫性气管支气管炎的病例。尽管克罗恩病累及呼吸道极为罕见,但我们对世界文献的回顾揭示了一些常见的临床病理特征。这些特征包括咳痰,胸部X光片除了一些外周受累外均正常。然而,支气管镜检查显示气管和支气管弥漫性炎症,有广泛散在的白色病变,而活检显示炎症细胞肉芽肿浸润。这种气管支气管炎通常对泼尼松治疗反应良好。