Eskişehir Osmangazi University, Faculty of Health Sciences, Department of Audiology, Türkiye.
Samsun Ondokuz Mayıs University, Faculty of Health Sciences, Department of Audiology, Kurupelit Campus, Samsun, Türkiye.
Am J Otolaryngol. 2023 Jul-Aug;44(4):103859. doi: 10.1016/j.amjoto.2023.103859. Epub 2023 Mar 22.
To determine whether exposure to intrauterine COVID-19 infection causes congenital or late-onset hearing loss in infants.
The hearing screening results of infants born in a tertiary hospital between March 2020 and April 2022 with and without a history of intrauterine exposure to COVID-19 infection (36 infants each) were retrospectively analyzed within one month after birth in all infants and additionally at six months after intrauterine COVID-19 infection exposure in the study group. The automated auditory brainstem response (AABR) test was used for the hearing evaluation.
The polymerase chain reaction test was negative in study group exposed to intrauterine COVID-19 infection. The number of infants admitted to the intensive care unit (ICU), and the length of ICU stay were significantly higher in this group (p < 0.01). Six infants (16.6 %) in the study group failed the first AABR test bilaterally, but five of these infants passed the second AABR test. A bilateral severe sensorineural hearing loss was detected in one infant (2.77 %). All the infants in the study group underwent the AABR test again at six months, and all infants, except this infant, passed the test. In the control group, five infants (13.88 %) failed the first AABR test bilaterally, but they all passed the second test.
Exposure to COVID-19 infection in the intrauterine period does not cause congenital or late-onset hearing loss (within six months) in infants; therefore, gestational COVID-19 infection is not a risk factor for infant hearing loss.
确定宫内 COVID-19 感染暴露是否会导致婴儿先天性或迟发性听力损失。
回顾性分析 2020 年 3 月至 2022 年 4 月在一家三级医院分娩的、有和无宫内 COVID-19 感染史（每组 36 例）的婴儿出生后 1 个月内的听力筛查结果，并在研究组中 COVID-19 宫内感染后 6 个月时对婴儿进行听力评估。采用自动听性脑干反应（AABR）测试进行听力评估。
研究组中 COVID-19 宫内感染暴露的聚合酶链反应检测结果为阴性。该组中入住重症监护病房（ICU）的婴儿数量和 ICU 停留时间明显更长（p<0.01）。研究组中有 6 名（16.6%）婴儿双侧首次 AABR 测试未通过，但其中 5 名婴儿通过了第二次 AABR 测试。1 名婴儿（2.77%）双侧严重感觉神经性听力损失。所有研究组婴儿均在 6 个月时再次接受 AABR 测试，除该婴儿外，所有婴儿均通过测试。在对照组中，有 5 名（13.88%）婴儿双侧首次 AABR 测试未通过，但他们均通过了第二次测试。
宫内 COVID-19 感染暴露不会导致婴儿先天性或迟发性听力损失（6 个月内）；因此，妊娠期 COVID-19 感染不是婴儿听力损失的危险因素。
