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接种新冠病毒疫苗后出现的耳鸣病例,一家机构的观察结果。

Tinnitus cases after COVID-19 vaccine administration, one institution's observations.

机构信息

University of North Carolina at Chapel Hill, 170 Manning Drive, Campus Box 7070, Chapel Hill, NC 27599-7070, United States of America.

出版信息

Am J Otolaryngol. 2023 Jul-Aug;44(4):103863. doi: 10.1016/j.amjoto.2023.103863. Epub 2023 Mar 24.

Abstract

OBJECTIVE

After the role out of the COVID-19 vaccine in the United States, there has been increase in case reports of tinnitus attributed to the vaccine reported. We present our institution's experience over the initial 13 month period the vaccines were available.

STUDY DESIGN

Retrospective chart review.

SETTING

Tertiary academic otology and general otolaryngology practice.

PATIENTS

Patients who received a COVID-19 vaccine and a tinnitus diagnosis code.

INTERVENTIONS

Observation, steroids (oral and intratympanic), diagnostic imaging and audiometry.

MAIN OUTCOME MEASURES

Patients who received a COVID-19 vaccine in the time frame of 12/1/2020-12/31/21 with a diagnosis of tinnitus, an audiogram, and at least one visit with one of our Otolaryngologists were included in the study. Twenty-seven of the 1254 patients identified met these criteria. The patients ranged in age from 41 to 84 years old including seven male and twenty female patients. Sixteen received the Pfizer vaccine, seven received the Moderna vaccine and four patients received the Janssen vaccine.

CONCLUSIONS

No definite correlation could be established between COVID-19 vaccine and tinnitus. Any concurrent sudden hearing loss should be treated as usual with oral or intratympanic steroids. Health care providers should be aware of the tinnitus onset and if new or recent onset, to refer for prompt audiogram and Otolaryngology evaluation.

摘要

目的

在美国推出 COVID-19 疫苗后,报告的与疫苗相关的耳鸣病例有所增加。我们介绍了我们机构在疫苗可用的最初 13 个月期间的经验。

研究设计

回顾性图表审查。

设置

三级学术耳科学和一般耳鼻喉科实践。

患者

接受 COVID-19 疫苗和耳鸣诊断代码的患者。

干预措施

观察、类固醇(口服和鼓室内)、诊断成像和听力测试。

主要观察指标

在 2020 年 12 月 1 日至 2021 年 12 月 31 日期间接受 COVID-19 疫苗且诊断为耳鸣、听力图和至少一次由我们的耳鼻喉科医生之一就诊的患者纳入研究。在 1254 名患者中,有 27 名符合这些标准。患者年龄从 41 岁到 84 岁不等,包括 7 名男性和 20 名女性患者。16 名患者接种了辉瑞疫苗,7 名接种了 Moderna 疫苗,4 名患者接种了 Janssen 疫苗。

结论

无法确定 COVID-19 疫苗与耳鸣之间存在明确的相关性。任何同时发生的突发性听力损失都应按照常规用口服或鼓室内类固醇治疗。医疗保健提供者应注意耳鸣的发作,如果是新出现或近期出现的,应及时进行听力测试和耳鼻喉科评估。

相似文献

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Clinical Practice Guideline: Sudden Hearing Loss (Update).临床实践指南:突发性聋(更新)。
Otolaryngol Head Neck Surg. 2019 Aug;161(1_suppl):S1-S45. doi: 10.1177/0194599819859885.

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