Department of Endocrinology, St James's Hospital, Dublin, Ireland; Department of Medicine, Trinity College Dublin, Ireland.
Department of Endocrinology, St James's Hospital, Dublin, Ireland; Department of Medicine, Trinity College Dublin, Ireland.
Best Pract Res Clin Endocrinol Metab. 2023 Jul;37(4):101760. doi: 10.1016/j.beem.2023.101760. Epub 2023 Mar 1.
The COVID-19 pandemic has had a profound global impact, affecting people's physical and mental health, and their social and economic circumstances. Mitigation measures have disproportionately affected women. Studies have reported menstrual cycle and psychological disturbance associated with the pandemic. Pregnancy is a risk factor for severe COVID-19 disease. Reports have also demonstrated associations between COVID-19 infection, vaccination and Long COVID syndrome and reproductive health disturbance. However, studies are limited and there may be significant geographical variation. Also there is bias amongst published studies, and menstrual cycle data was not included in COVID-19 and vaccine trials. Longitudinal population based studies are required. In this review we discuss existing data, along with recommendations for further research required in this area. We also discuss a pragmatic approach to women presenting with reproductive health disturbance in the era of the pandemic, encompassing a multi-system assessment of psychological, reproductive health and lifestyle.
COVID-19 大流行对全球产生了深远影响，影响了人们的身心健康以及社会和经济状况。缓解措施对女性的影响不成比例。研究报告称，与大流行相关的月经周期和心理障碍。妊娠是 COVID-19 严重疾病的一个危险因素。报告还表明，COVID-19 感染、疫苗接种和长 COVID 综合征与生殖健康障碍之间存在关联。然而，研究有限，可能存在显著的地域差异。此外，发表的研究存在偏见，COVID-19 和疫苗试验中并未纳入月经周期数据。需要进行纵向的基于人群的研究。在这篇综述中，我们讨论了现有数据，并就该领域进一步研究提出了建议。我们还讨论了在大流行时代应对生殖健康障碍的女性的实用方法，包括对心理、生殖健康和生活方式的多系统评估。
