Almuqbil Mansour, Al-Asmi Rama, AlRamly Samar, Hijazi Noor, Alotaibi Hailah, AlMubarak Ashwaq, AlAnezi Kholoud, Al-Rowaili Maha, Al-Yamani Mohammed, Duwaidi Badr Sami, Alshammari Dalal Rahil, Alabdulsalam Abdullah Mohammad, Almutairi Jamelah Abdualrhman, Alasmari Fayez Mohammad, Asdaq Syed Mohammed Basheeruddin
Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Department of Pharmacy Practice, College of Pharmacy, AlMaarefa University, Dariyah, Riyadh 13713, Saudi Arabia.
Vaccines (Basel). 2023 Feb 23;11(3):518. doi: 10.3390/vaccines11030518.
It is well known that vaccination is the best clinical approach for successfully controlling COVID-19 infection. Understanding the disparities in COVID-19 vaccination apprehension among parents in different societies is crucial for effectively implementing COVID-19 vaccination programs. This observational cross-sectional study was carried out in the Riyadh region of Saudi Arabia between February and April 2022. The validated questionnaire was shared with parents who had children between the ages of five and eleven years. The collected data were analyzed using descriptive and inferential statistical methods. Multinomial regression analysis was conducted to determine the factors significantly affecting vaccine-use decisions. Of the 699 participants, 83% of the mothers were between the ages of 35 and 44 years, 67% were university educated, and only 14% were healthcare workers. A large proportion of parents, with an age range of 18-34 years ( = 0.001), and those with a higher income group ( 0.014), demonstrated significant vaccine hesitancy. Further, parents who received one or two vaccination doses were significantly ( = 0.02) more hesitant than those who received more than two doses of the vaccine. Furthermore, a significantly ( = 0.002) high percentage of parents who follow the Ministry of Health (MOH) guidelines for personal preventive measures were hesitant about their children's vaccination. Concerns about side effects (31.4%) and a lack of safety data (31.2%) on the COVID-19 vaccines were the two most significant reasons for parents to develop vaccine hesitancy. Social media (24.3%), poor perceived immunity (16.3 %), and news articles (15.5%) were the top three contributors to this hesitancy. Vaccinated parents were 8.21 times more likely to be vaccination-hesitant than non-vaccinated parents. Additionally, parents with less education and a COVID-19-positive child at home increased the odds of vaccine hesitancy by 1.66 and 1.48 times, respectively. Overall, one-third of the parents were not prepared to vaccinate their children, and one-quarter of the respondents had not decided about vaccination. This study shows that parents in Riyadh are generally reluctant to vaccinate their children against COVID-19. As social media is a primary source of information for parents, public health professionals should utilize the platform to encourage parents to support vaccine acceptance.
众所周知，接种疫苗是成功控制新冠病毒感染的最佳临床方法。了解不同社会中家长对新冠疫苗接种的担忧差异，对于有效实施新冠疫苗接种计划至关重要。这项观察性横断面研究于2022年2月至4月在沙特阿拉伯利雅得地区开展。向有5至11岁孩子的家长发放了经过验证的问卷。使用描述性和推断性统计方法对收集到的数据进行分析。进行多项回归分析以确定显著影响疫苗使用决策的因素。在699名参与者中，83%的母亲年龄在35至44岁之间，67%接受过大学教育，只有14%是医护人员。很大一部分年龄在18至34岁之间的家长（ = 0.001）以及收入较高群体的家长（ 0.014）表现出显著的疫苗犹豫。此外，接种过一剂或两剂疫苗的家长比接种超过两剂疫苗的家长明显更犹豫（ = 0.02）。此外，很大一部分遵循卫生部个人预防措施指南的家长（ = 0.002）对其孩子接种疫苗犹豫不决。对新冠疫苗副作用的担忧（31.4%）和缺乏安全性数据（31.2%）是家长产生疫苗犹豫的两个最主要原因。社交媒体（24.3%）、较差的自我感知免疫力（16.3%）和新闻文章（15.5%）是导致这种犹豫的前三大因素。接种过疫苗的家长出现疫苗犹豫的可能性是非接种家长的8.21倍。此外，受教育程度较低且家中有新冠阳性孩子的家长，疫苗犹豫的几率分别增加了1.66倍和1.48倍。总体而言，三分之一的家长不准备为孩子接种疫苗，四分之一的受访者尚未决定是否接种。这项研究表明，利雅得的家长普遍不愿为孩子接种新冠疫苗。由于社交媒体是家长的主要信息来源，公共卫生专业人员应利用该平台鼓励家长支持疫苗接种。
