State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen 361102, China.
State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Biology, School of Life Sciences, Xiamen University, Xiamen 361102, China.
Viruses. 2023 Feb 21;15(3):596. doi: 10.3390/v15030596.
More than 600 million people worldwide have been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), resulting in the pandemic of coronavirus disease 2019 (COVID-19). In particular, new waves of COVID-19 caused by emerging SARS-CoV-2 variants pose new health risks to the global population. Nanotechnology has developed excellent solutions to combat the virus pandemic, such as ACE2-based nanodecoys, nanobodies, nanovaccines, and drug nanocarriers. Lessons learned and strategies developed during this battle against SARS-CoV-2 variants may also serve as inspiration for developing nanotechnology-based strategies to combat other global infectious diseases and their variants in the future.
全球已有超过 6 亿人感染严重急性呼吸综合征冠状病毒 2（SARS-CoV-2），导致 2019 年冠状病毒病（COVID-19）大流行。特别是由新型 SARS-CoV-2 变异株引起的 COVID-19 新一波浪潮给全球人口带来了新的健康风险。纳米技术为抗击病毒大流行提供了出色的解决方案，例如基于 ACE2 的纳米诱饵、纳米抗体、纳米疫苗和药物纳米载体。在这场抗击 SARS-CoV-2 变异株的战斗中吸取的经验教训和制定的策略也可能为未来开发基于纳米技术的策略提供灵感，以应对其他全球传染病及其变异株。
