Chiapuzzo A
J Int Med Res. 1979;7(1):57-60. doi: 10.1177/030006057900700109.
Twenty-four professional footballers suffering from recent soft-tissue injuries were included in a double-blind pilot trial comparing the efficacy and tolerability of indoprofen 800 mg/day and indomethacin 80 mg/day. Twelve subjects were allocated at random to each of the two drugs. Mean reduction of pain and swelling by the 3rd day of treatment was greater in the indoprofen group, as was the rate of disappearance of these symptoms, calculated in terms of t 1/2. A statistically significant (p less than 0.05) superiority of indoprofen versus indomethacin was, however, reached only for pain elicited by active movement. No adverse reactions were recorded with either drug.
24名近期患有软组织损伤的职业足球运动员被纳入一项双盲试验，比较每日800毫克布洛芬和每日80毫克吲哚美辛的疗效和耐受性。12名受试者被随机分配到两种药物组。治疗第3天，布洛芬组疼痛和肿胀的平均减轻程度更大，这些症状的消失率（以t 1/2计算）也是如此。然而，仅在主动运动引起的疼痛方面，布洛芬相对于吲哚美辛具有统计学显著优势（p<0.05）。两种药物均未记录到不良反应。
