Kim Min-Jae, Youn Young Chul, Paik Joonki
Department of Image, Chung-Ang University, Seoul, 06974, South Korea.
Department of Neurology, Chung-Ang University College of Medicine, Seoul, 06973, South Korea; Biomedical Research Institute, Chung-Ang University Hospital, Seoul, 06973, South Korea.
Neuroimage. 2023 May 15;272:120054. doi: 10.1016/j.neuroimage.2023.120054. Epub 2023 Mar 29.
For automatic EEG diagnosis, this paper presents a new EEG data set with well-organized clinical annotations called Chung-Ang University Hospital EEG (CAUEEG), which has event history, patient's age, and corresponding diagnosis labels. We also designed two reliable evaluation tasks for the low-cost, non-invasive diagnosis to detect brain disorders: i) CAUEEG-Dementia with normal, mci, and dementia diagnostic labels and ii) CAUEEG-Abnormal with normal and abnormal. Based on the CAUEEG dataset, this paper proposes a new fully end-to-end deep learning model, called the CAUEEG End-to-end Deep neural Network (CEEDNet). CEEDNet pursues to bring all the functional elements for the EEG analysis in a seamless learnable fashion while restraining non-essential human intervention. Extensive experiments showed that our CEEDNet significantly improves the accuracy compared with existing methods, such as machine learning methods and Ieracitano-CNN (Ieracitano et al., 2019), due to taking full advantage of end-to-end learning. The high ROC-AUC scores of 0.9 on CAUEEG-Dementia and 0.86 on CAUEEG-Abnormal recorded by our CEEDNet models demonstrate that our method can lead potential patients to early diagnosis through automatic screening.
对于自动脑电图诊断,本文提出了一个名为中央大学医院脑电图(CAUEEG)的新脑电图数据集,其具有条理清晰的临床注释,包括事件病史、患者年龄和相应的诊断标签。我们还为低成本、非侵入性诊断设计了两项可靠的评估任务,以检测脑部疾病:i)具有正常、轻度认知障碍和痴呆诊断标签的CAUEEG-痴呆症,以及ii)具有正常和异常标签的CAUEEG-异常。基于CAUEEG数据集,本文提出了一种新的全端到端深度学习模型,称为CAUEEG端到端深度神经网络(CEEDNet)。CEEDNet致力于以无缝可学习的方式整合脑电图分析的所有功能要素,同时限制不必要的人工干预。大量实验表明,由于充分利用了端到端学习,我们的CEEDNet与现有方法(如机器学习方法和Ieracitano-CNN(Ieracitano等人,2019年))相比,显著提高了准确率。我们的CEEDNet模型在CAUEEG-痴呆症上的ROC-AUC得分为0.9,在CAUEEG-异常上的得分为0.86,这表明我们的方法可以通过自动筛查引导潜在患者进行早期诊断。