Medical Laboratory Center, Chifeng Municipal Hospital/Chifeng Clinical College, Inner Mongolia Medical University, Chifeng 024000, P.R. China.
Medical Laboratory Center, Songshan Hospital, Chifeng 024000, P.R. China.
Oncol Rep. 2023 May;49(5). doi: 10.3892/or.2023.8537. Epub 2023 Mar 31.
Cancer is the leading cause of death globally and there is a worldwide cancer epidemic. Immunotherapy has emerged as a promising anticancer therapy. In particular, oncolytic viruses destroy cancer cells without destroying normal tissue via viral self‑replication and anti‑tumor immune responses, showing potential for cancer therapy. The present review discusses the role of the immune system in the treatment of tumor. The strategies for treating tumors are briefly introduced from aspects of active immunization and passive immunotherapy and the dendritic cell vaccines and oncolytic viruses are highlighted, as well as use of blood group A antigen in the treatment of solid tumors.
癌症是全球主要死因,存在全球癌症流行。免疫疗法已成为一种有前途的抗癌疗法。特别是溶瘤病毒通过病毒自我复制和抗肿瘤免疫反应破坏癌细胞而不破坏正常组织,显示出治疗癌症的潜力。本综述讨论了免疫系统在肿瘤治疗中的作用。从主动免疫和被动免疫治疗两个方面简要介绍了治疗肿瘤的策略,并重点介绍了树突状细胞疫苗和溶瘤病毒,以及 A 血型抗原在实体瘤治疗中的应用。