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1
Adjuvants in the induction of suppressor cells.诱导抑制性细胞中的佐剂。
Infect Immun. 1979 Feb;23(2):360-5. doi: 10.1128/iai.23.2.360-365.1979.
2
The adjuvant activity of mycobacterial RNA preparations and synthetic polynucleotides for induction of delayed hypersensitivity to purified protein derivative in guinea pigs.分枝杆菌RNA制剂和合成多核苷酸对豚鼠诱导对纯化蛋白衍生物迟发型超敏反应的佐剂活性。
J Immunol. 1975 Mar;114(3):1014-22.
3
Immunotherapy of guinea pig cancer with BCG.用卡介苗对豚鼠癌症进行免疫治疗。
Johns Hopkins Med J Suppl. 1974;3:121-30.
4
Relationship of macrophages to defective delayed-type hypersensitivity in B6/lpr mice.B6/lpr小鼠中巨噬细胞与缺陷性迟发型超敏反应的关系。
Clin Exp Immunol. 1986 Dec;66(3):599-605.
5
Kinetics of the humoral and cellular immune response of guinea pigs after injection of the synthetic adjuvant N-acetylmuramyl L-alanyl-D-isoglutamine: comparison with Freund complete adjuvant.豚鼠注射合成佐剂N-乙酰胞壁酰-L-丙氨酰-D-异谷氨酰胺后体液免疫和细胞免疫反应的动力学：与弗氏完全佐剂的比较
Infect Immun. 1978 Mar;19(3):966-71. doi: 10.1128/iai.19.3.966-971.1978.
6
Comparison of bcg strains for delayed hypersensitivity induction tested in vivo in guinea pigs and in vitro.用于在豚鼠体内和体外测试迟发型超敏反应诱导的卡介苗菌株比较
J Hyg Epidemiol Microbiol Immunol. 1982;26(4):435-44.
7
[The formation of delayed hypersensitivity to mycobacterial antigens].[对分枝杆菌抗原迟发型超敏反应的形成]
Zh Mikrobiol Epidemiol Immunobiol. 1991 Apr(4):66-8.
8
Suppression of BCG cell wall-induced delayed-type hypersensitivity by BCG pre-treatment. II. Induction of suppressor T cells by heat-killed BCG injection.卡介苗预处理对卡介苗细胞壁诱导的迟发型超敏反应的抑制作用。II. 热灭活卡介苗注射诱导抑制性T细胞
Immunology. 1982 Apr;45(4):655-61.
9
Guinea pig lung lavage cells after intranasal BCG sensitization.经鼻内卡介苗致敏后的豚鼠肺灌洗细胞。
Infect Immun. 1979 Sep;25(3):844-8. doi: 10.1128/iai.25.3.844-848.1979.
10
Studies on the composition of adjuvants which selectively enhance delayed-type hypersensitivity to lipid conjugated protein antigens.关于选择性增强对脂质结合蛋白抗原的迟发型超敏反应的佐剂成分的研究。
J Immunol. 1975 Jan;114(1 Pt 1):76-80.

引用本文的文献

1
A rapid passive hemagglutination method for demonstrating serum antibodies to Candida albicans.一种用于检测抗白色念珠菌血清抗体的快速被动血凝方法。
J Natl Med Assoc. 1981 Dec;73(12):1135-8.
2
Effect of route of Mycobacterium bovis BCG administration on induction of suppression of sporozoite immunity in rodent malaria.牛分枝杆菌卡介苗接种途径对啮齿类动物疟疾子孢子免疫抑制诱导的影响。
Infect Immun. 1981 Jan;31(1):408-12. doi: 10.1128/iai.31.1.408-412.1981.
3
Suppressor cell regulation of cell-mediated immune responses in renal infection in vitro modulation of suppressor cell activity.抑制细胞对肾感染中细胞介导免疫反应的调节 体外抑制细胞活性的调节
J Clin Invest. 1980 Oct;66(4):621-8. doi: 10.1172/JCI109897.
4
Induction of delayed type hypersensitivity against ultrasonicated Mycobacterium lepraemurium bacilli without simultaneous local reactivity against live bacilli or protective immunity.诱导针对超声处理的鼠麻风杆菌的迟发型超敏反应，同时对活杆菌无局部反应性或保护性免疫。
Clin Exp Immunol. 1983 Aug;53(2):319-27.
5
Mechanisms in the in vivo release of lymphokines: relationship of high and low responsiveness to other parameters of the immune response.体内淋巴因子释放的机制：高反应性和低反应性与免疫反应其他参数的关系。
Infect Immun. 1981 Oct;34(1):160-5. doi: 10.1128/iai.34.1.160-165.1981.
6
Regulation of the immune response by prostaglandins.前列腺素对免疫反应的调节
J Clin Immunol. 1983 Oct;3(4):295-315. doi: 10.1007/BF00915791.
7
Duration of adoptively transferred dengue virus-induced suppressor activity.过继转移的登革病毒诱导的抑制活性的持续时间。
Br J Exp Pathol. 1985 Jun;66(3):377-83.

本文引用的文献

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Impairment of immunological reactivity in guinea pigs by prior injection of adjuvant.预先注射佐剂对豚鼠免疫反应性的损害。
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2
THE IMMUNOLOGICAL BASIS OF ACQUIRED CELLULAR RESISTANCE.获得性细胞抗性的免疫学基础。
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Communications. "In vitro" cell reactions in delayed hypersensitivity.通讯。迟发型超敏反应中的“体外”细胞反应。
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4
Specific depression of delayed hypersensitivity to purified proteins, with relation to production of circulating antibody.对纯化蛋白迟发型超敏反应的特异性抑制，与循环抗体产生的关系。
Cell Immunol. 1973 Nov;9(2):242-50. doi: 10.1016/0008-8749(73)90075-0.
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T cell control of antibody production.T细胞对抗体产生的控制。
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6
Immunological enhancement: a study of blocking antibodies.免疫增强：封闭抗体的研究
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7
Specific suppression of delayed hypersensitivity: the possible presence of a suppressor B cell in the regulation of delayed hypersensitivity.迟发型超敏反应的特异性抑制：迟发型超敏反应调节中可能存在抑制性B细胞。
J Immunol. 1974 Dec;113(6):1716-25.
8
Regulation of the antibody response to type 3 pneumococcal polysaccharide. II. Mode of action of thymic-derived suppressor cells.对3型肺炎球菌多糖抗体应答的调节。II. 胸腺来源抑制性细胞的作用方式。
J Immunol. 1974 Jan;112(1):404-9.
9
Role of the thymus in tolerance. X. "Suppressor" activity of antigen-stimulated rat thymocytes transferred to normal recipients.胸腺在免疫耐受中的作用。十、转移至正常受体的抗原刺激大鼠胸腺细胞的“抑制”活性。
J Immunol. 1973 May;110(5):1290-9.
10
Depression of delayed hypersensitivity by pretreatment with Freund-type adjuvants. II. Mechanism of the phenomenon.弗氏佐剂预处理对迟发型超敏反应的抑制作用。II. 该现象的机制
Clin Exp Immunol. 1971 Aug;9(2):259-66.

诱导抑制性细胞中的佐剂。

Adjuvants in the induction of suppressor cells.

作者信息

Neta R, Salvin S B

出版信息

Infect Immun. 1979 Feb;23(2):360-5. doi: 10.1128/iai.23.2.360-365.1979.

DOI:10.1128/iai.23.2.360-365.1979
PMID:370015
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC414173/
Abstract

The effect of different mycobacterial adjuvants on the parameters of delayed hypersensitivity was investigated in strain 13 guinea pigs. The composition of the tubercle bacilli and the type of vehicle in which the antigen was presented determined the presence and extent of suppressor cell activity. When antigen was introduced in complete Freund adjuvant, both adherent and nonadherent cells had suppressive properties, with the suppressive effect demonstrable in vitro from 1 to 5 weeks after sensitization. Suppressor activity was indicated in vivo by a reduction of delayed footpad hypersensitivity in animals presensitized with complete Freund adjuvant.

摘要

在13号品系豚鼠中研究了不同分枝杆菌佐剂对迟发型超敏反应参数的影响。结核杆菌的组成以及抗原呈现时所用载体的类型决定了抑制细胞活性的存在及程度。当抗原用完全弗氏佐剂引入时，贴壁细胞和非贴壁细胞均具有抑制特性，致敏后1至5周在体外可证实其抑制作用。在用完全弗氏佐剂预致敏的动物中，足垫迟发型超敏反应降低表明体内存在抑制活性。