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越南 P.H.Hô(梧桐科)叶和干的抗菌活性和精油成分。

The antimicrobial activity and essential oil constituents of the leaves and trunks of P.H.Hô (Thymelaeceae) from Vietnam.

机构信息

Faculty of Forestry, Hue University of Agriculture and Forestry, Hue University, Hue City, Vietnam.

Phong Dien Nature Reserve, Phong Dien, Vietnam.

出版信息

Nat Prod Res. 2024 Feb-Mar;38(5):744-752. doi: 10.1080/14786419.2023.2196624. Epub 2023 Apr 2.

Abstract

The aim of the present paper was to report the chemical constituents and antimicrobial activity of essential hydrodistilled from the leaves and trunk of P.H.Hô (Thymelaeceae) from Vietnam. The essential oils were analysed comprehensively for their constituents by using Gas chromatography coupled with Mass spectrometry (GC/MS). The antimicrobial activity was determined by agar well diffusion and broth microdilution methods. The leaf essential oil comprised mainly of sesquiterpenes while fatty acids constitutes the bulk of the trunk essential oil. The main constituents of the leaf essential oil were β-caryophyllene (17.11%), α-selinene (10.99%), α-humulene (8.98%), β-selinene (8.01%), β-guaiol (6.69%) and β-elemene (5.65%). However, hexadecanoic acid (48.46%), oleic acid (19.80%) and tetradecanoic acid (5.32%) were the major compounds identified in the trunk essential oil. The trunk essential oil displayed antimicrobial activity against , with the minimum inhibitory concentration (MIC) value of about 256.0 µg/mL.

摘要

本研究报告的目的是报道从越南的 P.H.Hô(梧桐科)的叶和茎中提取的精油的化学成分和抗菌活性。通过气相色谱-质谱联用(GC/MS)全面分析了精油的成分。通过琼脂孔扩散法和微量肉汤稀释法测定了抗菌活性。叶精油主要由倍半萜组成,而脂肪酸则构成了茎精油的主要成分。叶精油的主要成分是 β-石竹烯(17.11%)、α-蛇麻烯(10.99%)、α-葎草烯(8.98%)、β-石竹烯(8.01%)、β-愈创木烯(6.69%)和 β-榄香烯(5.65%)。然而,在茎精油中鉴定出的主要化合物为十六烷酸(48.46%)、油酸(19.80%)和十四烷酸(5.32%)。茎精油对金黄色葡萄球菌表现出抗菌活性,最小抑菌浓度(MIC)值约为 256.0 µg/mL。

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