Hospital establishment specializing in infectious diseases El Hadi Flici, Algiers, Algeria.
Manchester Fungal Infection Group, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Mycoses. 2023 Jul;66(7):594-603. doi: 10.1111/myc.13585. Epub 2023 Apr 2.
Invasive and superficial fungal infections are increasingly reported in Algeria, testifying to the increase in their frequency in parallel with the increase in risk factors and the availability of diagnostic means, at least in university hospitals (CHU). The latter, located in the major northern cities, are equipped with high-performance diagnostic tools compared to hospitals in the interior of the country.
A comprehensive search of published and grey literature was undertaken. Prevalence and incidence of discrete fungal diseases were estimated using a deterministic modelling approach based on populations at risk. Population (2021) and major underlying disease risk groups were obtained from UNAIDS, WHO Tuberculosis and the international transplant registries as well as published data for asthma and COPD. The health service profile was summarised from national documentation.
Among the 43.6 million, including 12.9 million children, living in Algeria, the most prevalent fungal diseases are tinea capitis (>1.5 million), recurrent vaginal candidiasis (>500,000) and allergic fungal lung and sinus disorders (>110,000) and chronic pulmonary aspergillosis (>10,000). Life-threatening invasive fungal infection incidence includes 774 Pneumocystis pneumonia in AIDS, 361 cryptococcal meningitis, 2272 candidaemia and 2639 invasive aspergillosis cases. Fungal keratitis probably affects >6000 eyes each year.
Fungal infections are underestimated in Algeria because they are sought in patients with risk factors only after bacterial infections when they should be sought in parallel. The diagnosis is only accessible in hospitals in large cities and the work carried out in mycology is rarely published, making the estimation of the burden of these conditions difficult.
在阿尔及利亚，侵袭性和浅表真菌感染的报道越来越多，这表明随着危险因素的增加和诊断手段的可用性（至少在大学附属医院[CHU]中），真菌感染的频率也在增加。后者位于主要北部城市，配备了与该国内陆医院相比性能更高的诊断工具。
对已发表和灰色文献进行了全面检索。使用基于风险人群的确定性建模方法估计了离散真菌感染的患病率和发病率。从 UNAIDS、世界卫生组织结核病和国际移植登记处以及哮喘和 COPD 的已发表数据中获得了人口（2021 年）和主要潜在疾病风险群体。从国家文件中总结了卫生服务概况。
在 4360 万人口中，包括 1290 万儿童，在阿尔及利亚最常见的真菌感染疾病包括头癣（>150 万）、复发性阴道念珠菌病（>50 万）、变应性真菌性肺和鼻窦疾病（>11 万）和慢性肺曲霉病（>10000）。危及生命的侵袭性真菌感染发病率包括艾滋病中的 774 例肺囊虫肺炎、361 例隐球菌性脑膜炎、2272 例念珠菌血症和 2639 例侵袭性曲霉病。真菌性角膜炎每年可能影响>6000 只眼睛。
在阿尔及利亚，真菌感染被低估了，因为只有在出现细菌感染且存在危险因素的患者中才会寻求真菌感染，而实际上应该与细菌感染同时寻求。诊断仅在大城市的医院中可用，并且在真菌学方面开展的工作很少发表，这使得这些疾病负担的估计变得困难。
