Department of Dental Surgery, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India.
Department of Oral and Maxillofacial Surgery, Sri Sai Dental College and Research Institute, Srikakulam, Andhra Pradesh, India.
Indian J Dent Res. 2022 Oct-Dec;33(4):408-412. doi: 10.4103/ijdr.ijdr_627_22.
Mouth acts as a mirror for most of the underlying systemic diseases. Very few studies were done in south Indian population to observe the oral manifestations of human immunodeficiency virus (HIV) in relation to the cluster of differentiation 4 (CD4) count, and this study mainly highlights the presenting complaint of HIV patients during their dental visit. The study was aimed to determine the chief complaints of patients along with oral manifestations of HIV and correlate them to CD4 count.
One hundred consecutive HIV-positive patients were considered for the study. All the oral manifestations and the chief complaints along with the calculated CD4 counts were noted and the results were correlated. Spearman correlation was used for CD4 count and other oral manifestations.
The mean CD4 counts were 421 cells/mm with a standard deviation (SD) of 404.34 for the most common oral manifestation of burning mouth and 176.5 cells/mm for the least common manifestation of malignancies. The CD4 count ranged from 120 to 1100 cells/mm. The mean age and CD4 count were 38 years and 398.86, respectively. There was a statistically significant correlation with candidiasis and gingivitis, and the rest of the conditions were insignificant.
The study results suggest that the chief complaint of presentation of an HIV-positive patient is pain due to carious teeth/abscess followed by burning mouth, with candidiasis being the most common disease.
口腔是大多数潜在系统性疾病的镜子。很少有研究在印度南部人群中观察人类免疫缺陷病毒 (HIV) 与分化群 4 (CD4) 计数的关系，本研究主要强调了 HIV 患者在牙科就诊时的主要主诉。本研究旨在确定患者的主要主诉以及 HIV 的口腔表现，并将其与 CD4 计数相关联。
考虑了 100 名连续的 HIV 阳性患者进行研究。记录了所有的口腔表现、HIV 的主要主诉以及计算出的 CD4 计数，并对结果进行了相关性分析。使用 Spearman 相关分析了 CD4 计数和其他口腔表现。
最常见的口腔表现为烧灼感，平均 CD4 计数为 421 个细胞/mm，标准差（SD）为 404.34；最不常见的表现为恶性肿瘤，CD4 计数为 176.5 个细胞/mm。CD4 计数范围为 120 至 1100 个细胞/mm。平均年龄和 CD4 计数分别为 38 岁和 398.86。CD4 计数与念珠菌病和牙龈炎之间存在统计学显著相关性，而其余情况则无显著相关性。
研究结果表明，HIV 阳性患者就诊的主要主诉是龋齿/脓肿引起的疼痛，其次是烧灼感，而念珠菌病是最常见的疾病。
