Alzuhairy Sultan
Department of Ophthalmology, College of Medicine, Qassim University, Buraidah, Saudi Arabia.
Oman J Ophthalmol. 2023 Feb 21;16(1):82-87. doi: 10.4103/ojo.ojo_215_22. eCollection 2023 Jan-Apr.
To present changes in transpalpebral intraocular pressure (tpIOP) in eyes after transepithelial photorefractive keratectomy (TPRK) in myopic Saudi patients and its determinants.
This one-armed cohort included the myopic eyes of Saudi adolescents treated with TPRK in 2020-2021. The difference in tpIOP before surgery, 1 week after surgery, and 1 month after surgery using Diaton was the main outcome. Central corneal thickness (CCT), myopia grade, gender, age, and corneal epithelial thickness before surgery were independent factors. Matched-pair analysis was conducted. The determinants of tpIOP post-TPRK were studied.
Our cohort included 193 eyes of 97 participants (25.6 ± 5.8 years). Mild, moderate, and severe myopia were present in 93, 79, and 21 eyes, respectively. tpIOP was 22 mmHg or more in 5 and 8 eyes at 1-week and 1-month follow-up, respectively. The change in tpIOP ranged from - 7.00 to + 11.0 mmHg at 1 week and - 8.0 to + 26.0 mmHg at 1 month. The median change of CCT at 1 month was 59 μ. Change in tpIOP was not correlated with change in CCT at 1 month ( = -0.107, Pearson = 0.14). Change of tpIOP was significantly correlated to spherical equivalent (SE) before surgery (matched-pair < 0.001). SE (Mann-Whitney U = 0.02) and tpIOP (Mann-Whitney U = 0.02) before TPRK were significantly correlated to tpIOP >22 mmHg after TPRK.
The changes in tpIOP following refractive surgery correlate to the refractive status of the eye and tpIOP before surgery.
呈现沙特近视患者经上皮准分子激光角膜切削术（TPRK）后经睑眼压（tpIOP）的变化及其影响因素。
该单臂队列研究纳入了2020年至2021年接受TPRK治疗的沙特青少年近视患者的眼睛。使用Diaton测量术前、术后1周和术后1个月的tpIOP差异作为主要观察指标。中央角膜厚度（CCT）、近视度数、性别、年龄和术前角膜上皮厚度为独立因素。进行配对分析。研究TPRK术后tpIOP的影响因素。
我们的队列包括97名参与者的193只眼睛（年龄25.6±5.8岁）。分别有93只、79只和21只眼睛存在轻度、中度和重度近视。在1周和1个月随访时，分别有5只和8只眼睛的tpIOP为22 mmHg或更高。tpIOP在1周时的变化范围为-7.00至+11.0 mmHg，在1个月时为-8.0至+26.0 mmHg。1个月时CCT的中位数变化为59μm。1个月时tpIOP的变化与CCT的变化无相关性（r=-0.107，Pearson检验P=0.14）。tpIOP的变化与术前等效球镜度（SE）显著相关（配对分析P<0.001）。TPRK术前的SE（Mann-Whitney U检验P=0.02）和tpIOP（Mann-Whitney U检验P=0.02）与TPRK术后tpIOP>22 mmHg显著相关。
屈光手术后tpIOP的变化与眼睛的屈光状态和术前tpIOP相关。
