Ventura Camila V, Aragão Itamara, Ventura Liana O
Department of Ophthalmology, Altino Ventura Foundation, Recife, Brazil.
Department of Ophthalmology, HOPE Eye Hospital, Recife, Brazil.
J Vitreoretin Dis. 2020 Nov 25;5(5):425-430. doi: 10.1177/2474126420972256. eCollection 2021 Sep-Oct.
We describe subtle macular changes that were detected by high-magnification color fundus imaging in infants with congenital Zika syndrome.
This series included 4 infants (age: 1.4 ± 0.1 years [range, 1.3-1.5 years]) who were serologically confirmed with congenital Zika syndrome, examined under anesthesia, and underwent fundus examination and color fundus documentation. The fundus images were captured using 130° and 80° field lenses. Fluorescein angiography confirmed macular lesions.
Wide-angle color fundus images detected unilateral retinal findings in all 4 infants. Chorioretinal atrophy was identified in 2 eyes (25%) of 2 infants (50%) and pigment mottling in 3 eyes (37.5%) of 2 infants (50%). High-magnification imaging revealed subtle macular changes in the contralateral eyes of the 4 infants that were confirmed by fluorescein angiography imaging.
High-magnification fundus imaging can be effective and reliable in revealing and documenting subtle structural changes in the macula of infants with congenital Zika syndrome.
我们描述了在先天性寨卡综合征婴儿中通过高倍彩色眼底成像检测到的细微黄斑变化。
本系列研究纳入了4名婴儿（年龄：1.4±0.1岁[范围1.3 - 1.5岁]），这些婴儿经血清学确诊为先天性寨卡综合征，在麻醉状态下接受检查，并进行了眼底检查和彩色眼底记录。使用130°和80°视野镜头拍摄眼底图像。荧光素血管造影证实了黄斑病变。
广角彩色眼底图像在所有4名婴儿中均检测到单侧视网膜病变。2名婴儿（50%）的2只眼睛（25%）出现脉络膜视网膜萎缩，2名婴儿（50%）的3只眼睛（37.5%）出现色素沉着。高倍成像显示4名婴儿对侧眼存在细微黄斑变化，荧光素血管造影成像证实了这些变化。
高倍眼底成像在揭示和记录先天性寨卡综合征婴儿黄斑的细微结构变化方面可能是有效且可靠的。
