鼠伤寒沙门氏菌中N-乙酰谷氨酸合成的调控
Regulation of N-acetylglutamate synthesis in Salmonella typhimurium.
作者信息
Abdelal A T, Nainan O V
出版信息
J Bacteriol. 1979 Feb;137(2):1040-2. doi: 10.1128/jb.137.2.1040-1042.1979.
Abstract
N-Acetylglutamate synthase was purified to homogeneity from Salmonella typhimurium. The enzyme is subject to repression and feedback inhibition by arginine. Inhibition studies indicated that arginine exerts its effect primarily by reducing the affinity of the enzyme for glutamate.
摘要
从鼠伤寒沙门氏菌中纯化出了N-乙酰谷氨酸合酶，且该酶已达到同质状态。该酶受到精氨酸的阻遏和反馈抑制。抑制研究表明，精氨酸主要通过降低该酶对谷氨酸的亲和力来发挥其作用。
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本文引用的文献
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J Biol Chem. 1956 Jan;218(1):97-106.
2
Enzymatic synthesis of acetylglutamate by mammalian liver preparations and its stimulation by arginine.哺乳动物肝脏制剂对乙酰谷氨酸的酶促合成及其受精氨酸的刺激作用。
Biochem Biophys Res Commun. 1971 Sep;44(5):1117-24. doi: 10.1016/s0006-291x(71)80201-2.
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N-acetylglutamate synthetase of Pseudomonas aeruginosa. An assay in vitro and feedback inhibition by arginine.铜绿假单胞菌的N-乙酰谷氨酸合成酶。体外测定及精氨酸的反馈抑制作用
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8
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