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Perfluorocarbon liquid manipulation of high-density intraocular foreign bodies.高密度眼内异物的全氟碳液体处理
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本文引用的文献

1
Perfluorocarbon induces alveolar epithelial cell response through structural and mechanical remodeling.全氟碳化合物通过结构和力学重塑诱导肺泡上皮细胞反应。
Biomech Model Mechanobiol. 2018 Aug;17(4):961-973. doi: 10.1007/s10237-018-1005-z. Epub 2018 Feb 15.
2
A rare case of perfluoro-n-octane in the orbit following vitreoretinal surgery.玻璃体视网膜手术后眼眶内出现全氟正辛烷的罕见病例。
Can J Ophthalmol. 2017 Jun;52(3):e113-e115. doi: 10.1016/j.jcjo.2017.01.002. Epub 2017 Mar 2.
3
Bilateral subcutaneous emphysema from pressurized infusion during pars plana vitrectomy: a case report.玻璃体切割术期间加压输注导致双侧皮下气肿:一例报告
Retin Cases Brief Rep. 2012 Winter;6(1):22-4. doi: 10.1097/ICB.0b013e3181f98cea.
4
Perfluorocarbon liquid: its application in vitreoretinal surgery and related ocular inflammation.全氟碳液体:其在玻璃体视网膜手术及相关眼部炎症中的应用
Biomed Res Int. 2014;2014:250323. doi: 10.1155/2014/250323. Epub 2014 Mar 30.
5
Inflammation induced by perfluorocarbon liquid: intra- and postoperative use.全氟碳液体诱导的炎症:术中及术后应用
Biomed Res Int. 2014;2014:907816. doi: 10.1155/2014/907816. Epub 2014 Mar 24.
6
[Perfluoro-n-octane in orbital cavity after posterior vitrectomy and suture of eye perforating injury: case report].[玻璃体切除术后及眼球穿孔伤缝合术后眶内全氟正辛烷:病例报告]
Arq Bras Oftalmol. 2011 Jul-Aug;74(4):296-9. doi: 10.1590/s0004-27492011000400015.
7
Perfluorocarbon-based oxygen carriers: review of products and trials.基于全氟碳的氧载体:产品和试验回顾。
Artif Organs. 2010 Aug;34(8):622-34. doi: 10.1111/j.1525-1594.2009.00944.x.
8
Retained perfluoron postvitreoretinal surgery causing secondary open-angle glaucoma.玻璃体视网膜手术后全氟化物残留导致继发性开角型青光眼。
Can J Ophthalmol. 2008 Jun;43(3):372. doi: 10.3129/i08-047.
9
Perfluorocarbon compounds as vehicles for pulmonary drug delivery.全氟碳化合物作为肺部药物递送的载体。
Expert Opin Drug Deliv. 2007 May;4(3):247-62. doi: 10.1517/17425247.4.3.247.
10
Corneal toxicity and inflammation secondary to retained perfluorodecalin.全氟萘烷残留继发的角膜毒性和炎症
Am J Ophthalmol. 2005 Aug;140(2):322-3. doi: 10.1016/j.ajo.2005.01.034.

玻璃体切除术后眶周皮下注射全氟丙烷耐受性良好。

Periorbital Subcutaneous Perfluoron Is Well Tolerated Following Intravitreal Surgery.

作者信息

Larochelle Ryan D, Shields Ryan A, Erickson Benjamin P, Silva A Ruwan

机构信息

Department of Ophthalmology, University of Colorado, Denver, CO, USA.

Department of Ophthalmology, Beaumont Health System, Royal Oak, MI, USA.

出版信息

J Vitreoretin Dis. 2020 Jan 21;4(4):337-339. doi: 10.1177/2474126419899768. eCollection 2020 Jul-Aug.

DOI:10.1177/2474126419899768
PMID:37009182
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9976109/
Abstract

PURPOSE

Perfluorocarbon liquids (PFCLs) are well tolerated in intraocular surgery, but chronic exposure can cause inflammation. PFCL leakage into the orbit without significant sequelae has been reported, but PFCL leakage into the preseptal subcutaneous tissues has not been described.

METHODS

A case report is presented.

RESULTS

A 46-year-old man presented with hand motion vision from a ruptured globe and retained intraocular foreign body. Intraoperatively, the foreign body could not be removed, and PFCL extravasated from the posterior globe rupture. Postoperative imaging revealed hyperdense material in the orbit, lids, and superficial adnexal tissues. The patient tolerated the retained PFCL, and imaging 10 months later demonstrated interval resorption. The patient eventually developed ocular siderosis and underwent transconjunctival orbitotomy with foreign body extraction. Two years following the initial injury, his vision remained stable at 20/40 without further sequelae.

CONCLUSIONS

PFCL is well tolerated in the extraocular space and may resorb with conservative management.

摘要

目的

全氟碳化合物液体(PFCLs)在眼内手术中耐受性良好,但长期接触可引起炎症。有报道称PFCL漏入眼眶且无明显后遗症,但PFCL漏入眶隔前皮下组织的情况尚未见描述。

方法

本文报告一例病例。

结果

一名46岁男性因眼球破裂和眼内异物残留而仅有手动视力。术中,异物无法取出,PFCL从眼球后部破裂处渗出。术后影像学检查显示眼眶、眼睑和浅表附属器组织中有高密度物质。患者耐受了残留的PFCL,10个月后的影像学检查显示其逐渐吸收。该患者最终出现眼铁质沉着症,并接受了经结膜眶切开异物取出术。初始损伤两年后,他的视力稳定在20/40,无进一步后遗症。

结论

PFCL在眼外间隙耐受性良好,保守治疗可能会使其吸收。