性别与财富不平等对老年人阿尔茨海默病的影响：一项全球研究。
The influence of gender and wealth inequality on Alzheimer's disease among the elderly: A global study.
作者信息
Yu Shoukai, Qian Lingmei, Ma Jun
机构信息
Hongqiao International Institute of Medicine, Tongren Hospital, School of Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
出版信息
Heliyon. 2023 Mar 20;9(4):e14677. doi: 10.1016/j.heliyon.2023.e14677. eCollection 2023 Apr.
Abstract
This study was designed to explore the relationship between Alzheimer's disease (AD) rates and socioeconomic conditions in 120 countries. We used mixed effect models to investigate the relationship between the rates of AD and socioeconomic data. This study is among the first studies to put forward statistical evidence of a significant association between AD and other dementias among the elderly and socioeconomic inequality. These findings could help to inform the policies to be designed to improve the quality of interventions for AD.
摘要
本研究旨在探究120个国家中阿尔茨海默病（AD）发病率与社会经济状况之间的关系。我们使用混合效应模型来研究AD发病率与社会经济数据之间的关系。本研究是最早提出统计学证据证明老年人中AD及其他痴呆症与社会经济不平等之间存在显著关联的研究之一。这些发现有助于为旨在提高AD干预质量而设计的政策提供参考。
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本文引用的文献
1
The Health Equity Framework: A Science- and Justice-Based Model for Public Health Researchers and Practitioners.健康公平框架：面向公共卫生研究人员和从业者的科学与公正为本的模型。
Health Promot Pract. 2021 Nov;22(6):741-746. doi: 10.1177/1524839920950730. Epub 2020 Aug 19.
2
Modifiable Risk Factors Explain Socioeconomic Inequalities in Dementia Risk: Evidence from a Population-Based Prospective Cohort Study.可改变的风险因素解释了痴呆风险的社会经济不平等：来自基于人群的前瞻性队列研究的证据。
J Alzheimers Dis. 2019;71(2):549-557. doi: 10.3233/JAD-190541.
3
Gender inequality and restrictive gender norms: framing the challenges to health.性别不平等和限制性别规范：健康面临的挑战。
Lancet. 2019 Jun 15;393(10189):2440-2454. doi: 10.1016/S0140-6736(19)30652-X. Epub 2019 May 30.
4
Health and Socioeconomic Inequities as Contributors to Brain Health.健康与社会经济不平等对大脑健康的影响
JAMA Neurol. 2019 Jun 1;76(6):633-634. doi: 10.1001/jamaneurol.2019.0362.
5
State inequality, socioeconomic position and subjective cognitive decline in the United States.美国的国家不平等、社会经济地位与主观认知衰退
SSM Popul Health. 2019 Feb 22;7:100357. doi: 10.1016/j.ssmph.2019.100357. eCollection 2019 Apr.
6
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7
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8
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9
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10
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Ann Epidemiol. 2016 Apr;26(4):238-40. doi: 10.1016/j.annepidem.2016.02.003. Epub 2016 Mar 3.
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