Bariatric Surgery, Zuyderland Medical Center, Henri Dunantstraat 5, 6419, Heerlen, PC, Netherlands.
Dutch Obesity Clinic South, John F. Kennedylaan 301, 6419, Heerlen, XZ, Netherlands.
Obes Surg. 2023 Jun;33(6):1668-1675. doi: 10.1007/s11695-023-06573-8. Epub 2023 Apr 3.
Some patients with overweight or obesity are not eligible for surgery according to international guidelines or do not wish a surgical intervention. For these patients, different treatment options are being explored. In this study, we examined the effectiveness of the swallowable intragastric balloon (IB) combined with lifestyle coaching, in patients living with overweight and obesity.
A retrospective data study was conducted on patients with a swallowable IB placement between December 2018 and July 2021, combined with a 12-month coaching program. Before balloon placement, patients underwent multidisciplinary screening. The IB was swallowed and filled with fluid once in the stomach and naturally excreted around 16 weeks.
A total of 336 patients, 71.7% female, were included with a mean age of 45.7 (±11.7) years. Mean baseline weight and BMI were 107.54 (±19.16) kg and 36.1 (±5.02) kg/m. After 1 year, the mean total weight loss was 11.0% (±8.4). The mean placement duration was 13.1 (±2.82) min, and in 43.7%, a stylet was used to facilitate placement. The most common symptoms were nausea (80.4%) and gastric pain (80.3%). In the majority of patients, complaints were resolved within a week. The early deflation of the balloon occurred in 8 patients (2.4%) of which one showed symptoms suggesting a gastric outlet obstruction.
Given the low rate of long-term complaints while providing a positive effect on weight loss, we conclude that the swallowable intragastric balloon, combined with lifestyle coaching, is a safe and effective treatment option for patients living with overweight and obesity.
根据国际指南，一些超重或肥胖患者不符合手术条件，或不愿接受手术干预。对于这些患者，正在探索不同的治疗选择。本研究旨在评估可吞咽胃内球囊（IB）联合生活方式指导在超重和肥胖患者中的有效性。
对 2018 年 12 月至 2021 年 7 月间接受可吞咽 IB 置入术并联合 12 个月教练计划的患者进行回顾性数据分析。在 IB 置入前，患者需接受多学科筛查。IB 一旦被吞咽进入胃部，就会被注满液体并在大约 16 周后自然排出。
共纳入 336 例患者，71.7%为女性，平均年龄为 45.7（±11.7）岁。平均基线体重和 BMI 分别为 107.54（±19.16）kg 和 36.1（±5.02）kg/m²。1 年后，平均总减重为 11.0%（±8.4）。平均置管时间为 13.1（±2.82）min，其中 43.7%的患者使用了引导钢丝以方便置管。最常见的症状是恶心（80.4%）和胃痛（80.3%）。大多数患者的症状在一周内得到缓解。8 例（2.4%）患者的球囊早期排空，其中 1 例出现提示胃出口梗阻的症状。
鉴于长期并发症发生率低且对体重减轻有积极影响，我们认为可吞咽胃内球囊联合生活方式指导是超重和肥胖患者的一种安全有效的治疗选择。
