慢性乙型肝炎与 HIV 合并感染。
Chronic hepatitis B and HIV coinfection.
机构信息
University of Washington, Seattle, WA, USA.
出版信息
Top Antivir Med. 2023 Mar 31;31(1):14-22.
Abstract
Hepatitis B virus (HBV) infection is common among people with HIV owing to shared modes of viral transmission. Compared with individuals with HBV infection alone, people with HIV/HBV coinfection experience an accelerated progression of liver disease, including increased risks for hepatocellular carcinoma, liver-related mortality, and all-cause mortality. Therefore, HBV screening and appropriate treatment are crucial for people with HIV. This article reviews the epidemiology, natural history, and management of HIV/HBV coinfection, as well as recommendations for prevention of HBV infection among people with HIV.
摘要
乙型肝炎病毒 (HBV) 感染在 HIV 感染者中很常见，因为它们具有共同的病毒传播模式。与单独感染 HBV 的个体相比，HIV/HBV 合并感染的个体肝脏疾病进展更快，包括肝癌、与肝脏相关的死亡率和全因死亡率的风险增加。因此，HBV 筛查和适当的治疗对于 HIV 感染者至关重要。本文综述了 HIV/HBV 合并感染的流行病学、自然史和管理，以及预防 HIV 感染者感染 HBV 的建议。
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