Kibriya Sabahath, Srinivasan Ila, Setty Jyothsna V, Anu S, Khan Bisma S
Department of Pediatric Dentistry, Mathrusri Ramabai Ambedkar Dental College & Hospital, Bengaluru, Karnataka, India.
Int J Clin Pediatr Dent. 2023 Jan-Feb;16(1):54-59. doi: 10.5005/jp-journals-10005-2494.
Assessing the efficacy of cocoa bean husk extract (CBHE) particles with different vehicles as a mouthrinse in children aged 7-12 years in comparison to chlorhexidine (CHX) and sodium fluoride (NaF) mouthrinse.
A total of 80 children aged 7-12 years residing at a residential school/orphanage in Bengaluru city were selected and randomly allocated into five groups-group I: 0.1% CBHE with distilled water (DW); group II: 0.1% CBHE with Ringer's lactate (RL); group III: 0.12% CHX; group IV: 0.1% CBHE with normal saline (NS); and group V: 0.05% NaF. A Simplified Oral Hygiene Index (OHI-S) was recorded, salivary pH was assessed, and unstimulated saliva samples were collected at baseline (BL) after 30 minutes of rinsing on day 7 and day 14. These saliva samples were subjected to microbiological analysis, and all the data from five groups at four different time intervals was tabulated and statistically evaluated.
Nearly 0.1% CBHE with NS as vehicle showed maximum antibacterial properties among all the groups at all time intervals. The addition of RL to CBHE provided better anti-plaque efficacy than 0.1% CBHE with DW and 0.12% CHX mouthwash. All three combinations of 0.1% CBHE and 0.12% CHX mouthwash proved to be better anti-plaque agents than 0.05% NaF. Improving the preparation of CBHE mouthwash by using NS, RL, and with the addition of saccharin sodium also improved the patient's compliance.
Thus, preparing chocolate/CBHE mouthwash with NS or RL instead of plain DW increased the salivary pH, anti-plaque efficacy, and antibacterial property by reducing growth.
Cocoa bean husk extract (CBHE) mouthwash is a better anticariogenic and nonalcoholic mouthwash compared to CHX and NaF, which can be safely used in children as a routine oral rinse and also for those with gingivitis and high-risk of caries.
Kibriya S, Srinivasan I, Setty JV, Characterization of Cocoa Bean Husk Extract Particles and its Comparison as a Mouthrinse with Different Vehicles in Children aged 7-12 Years. Int J Clin Pediatr Dent 2023;16(1):54-59.
评估与洗必泰（CHX）和氟化钠（NaF）漱口水相比，不同载体的可可豆皮提取物（CBHE）颗粒作为漱口水对7至12岁儿童的疗效。
选取80名居住在班加罗尔市寄宿学校/孤儿院的7至12岁儿童，随机分为五组——第一组：0.1% CBHE加蒸馏水（DW）；第二组：0.1% CBHE加乳酸林格液（RL）；第三组：0.12% CHX；第四组：0.1% CBHE加生理盐水（NS）；第五组：0.05% NaF。记录简化口腔卫生指数（OHI-S），评估唾液pH值，并在第7天和第14天漱口30分钟后的基线（BL）采集非刺激性唾液样本。对这些唾液样本进行微生物分析，并将五组在四个不同时间间隔的所有数据列表并进行统计学评估。
在所有时间间隔内，以NS为载体的近0.1% CBHE在所有组中显示出最大的抗菌性能。在CBHE中添加RL比0.1% CBHE加DW和0.12% CHX漱口水具有更好的抗牙菌斑效果。0.1% CBHE和0.12% CHX漱口水的所有三种组合都被证明是比0.05% NaF更好的抗牙菌斑剂。通过使用NS、RL以及添加糖精钠来改进CBHE漱口水的制剂也提高了患者的依从性。
因此，用NS或RL而非普通DW制备巧克力/CBHE漱口水可提高唾液pH值、抗牙菌斑效果和抗菌性能，同时减少细菌生长。
与CHX和NaF相比，可可豆皮提取物（CBHE）漱口水是一种更好的防龋和非酒精性漱口水，可安全地用于儿童日常口腔冲洗，也适用于患有牙龈炎和高龋齿风险的儿童。
Kibriya S, Srinivasan I, Setty JV, 《可可豆皮提取物颗粒的特性及其作为漱口水与不同载体在7至12岁儿童中的比较》。《国际临床儿科牙科学杂志》2023；16(1):54 - 59。
