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可可豆皮、生姜和洗必泰漱口水对降低唾液中变形链球菌和乳酸菌数量的比较评价:一项随机对照试验。

Comparative Evaluation of Cocoa Bean Husk, Ginger and Chlorhexidine Mouth Washes in the Reduction of Steptococcus Mutans and Lactobacillus Count in Saliva: A Randomized Controlled Trial.

作者信息

S Shrimathi, Kemparaj Umesh, Umesh Sangeeta, Karuppaiah Muthu, Pandian Palanivel, A Krishnaveni

机构信息

Public Health Dentistry, Best Dental Science College and Hospital, Madurai, IND.

Pharmacognosy, College of Pharmacy, Madurai Medical College, Madurai, IND.

出版信息

Cureus. 2019 Jun 21;11(6):e4968. doi: 10.7759/cureus.4968.

Abstract

Introduction Dental caries is a ubiquitous bacterial infection that has afflicted people for years. () are markers of dental caries and the population of in the saliva is directly related to the number of surfaces colonized by them. Any intervention that can inhibit their growth and survival will negatively impact the initiation and progress of caries. Various antimicrobial agents have been tested against these microorganisms. The goal of this study was to assess the efficacy of cocoa bean husk, ginger, and chlorhexidine mouth rinse on and Lactobacillus. Materials and methods We conducted a randomized controlled trial involving patients aged 18 to 25 years from July to September 2018. The study population was allocated into three groups. Each group received either cocoa bean, ginger, or chlorhexidine mouth rinses. The study followed a Latin square design. Study participants were instructed to use the assigned mouth rinse once daily for seven days. We collected saliva samples to measure and Lactobacillus populations. Results Cocoa bean husk and chlorhexidine rinses produced a significant reduction of (p < 0.05). The ginger-based rinse significantly reduced the Lactobacillus population (p < 0.05). Conclusion Our findings indicate these natural mouth rinses offer promising anticariogenic and antiplaque efficacy as cost-effective alternatives to traditional mouth rinses.

摘要

引言

龋齿是一种普遍存在的细菌感染,多年来一直困扰着人们。()是龋齿的标志物,唾液中()的数量与被它们定植的牙面数量直接相关。任何能够抑制它们生长和存活的干预措施都会对龋齿的发生和发展产生负面影响。已经针对这些微生物测试了各种抗菌剂。本研究的目的是评估可可豆壳、生姜和洗必泰漱口水对()和乳酸杆菌的功效。

材料和方法

我们于2018年7月至9月对18至25岁的患者进行了一项随机对照试验。研究人群被分为三组。每组分别接受可可豆、生姜或洗必泰漱口水。该研究采用拉丁方设计。研究参与者被指示每天使用指定的漱口水一次,持续七天。我们收集唾液样本以测量()和乳酸杆菌数量。

结果

可可豆壳漱口水和洗必泰漱口水使()显著减少(p < 0.05)。以生姜为基础的漱口水使乳酸杆菌数量显著减少(p < 0.05)。

结论

我们的研究结果表明,这些天然漱口水作为传统漱口水的经济有效替代品,具有良好的防龋和抗牙菌斑功效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6cc/6701906/62a0488bc1d1/cureus-0011-00000004968-i01.jpg

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