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、和氯己定漱口水对儿童口腔内变形链球菌和远缘链球菌的抗菌效果:一项对比研究。

Antimicrobial Efficacy of , , and Chlorhexidine Mouthwashes on and in Children: A Comparative Study.

作者信息

Kajjari Shweta, Vanishree B K, Janardhanan Sruthi, Patil Vidyavathi H, Uppin Chaitanya, Hugar Shivayogi M

机构信息

Department of Pediatric and Preventive Dentistry, KLE V. K. Institute of Dental Sciences, KLE Academy of Higher Education and Research, Belagavi, Karnataka, India.

Department of Pediatric and Preventive Dentistry, M. A. Rangoonwala College of Dental Sciences & Research Centre, Pune, Maharashtra, India.

出版信息

Int J Clin Pediatr Dent. 2024 Apr;17(Suppl 1):S78-S83. doi: 10.5005/jp-journals-10005-2795.

Abstract

BACKGROUND

Herbal medicines are both promotive and preventive in inhibiting dental caries. Most commonly used natural plant extracts like mango () and pudina () as an entire or together are scientifically well proven to be safe and effective against various oral health problems, especially in preventing dental caries and periodontal diseases.

AIM

The present study aims to comparatively evaluate the effect of , , and Chlorhexidine (CHX) (0.2%) mouthwashes on () and () in children.

MATERIALS AND METHODS

By random allocation, 45 healthy children were selected between the age-group of 7 and 10 years of both genders from a residential school. They were divided into three study groups of 15 in each; group I-CHX (control group), group II- mouthwash, and group III- mouthwash. Stimulated whole saliva sample collected for the amount of colony forming units and cultured for and . The data was tabulated, and statistical analysis was done with one-way variance analysis of the variance (ANOVA), Tukey's honestly significant difference (HSD) test, and Bonferroni and Kruskal-Wallis test.

RESULTS

(group II) and (group III) showed a significant reduction of salivary counts at baseline, 14th day, and 21st day period and minimal effect on for . Among the three types of mouthwash, the CHX was the most superior; it showed a statistically significant reduction overall. When compared to with , showed a statistically significant reduction in and and had an almost equivocal effect like CHX.

CONCLUSION

Both herbal mouthwashes had a significant reduction in the and in children. So, it can be considered an active ingredient in mouthwashes. It may serve as a natural antimicrobial mouthwash with no adverse effects.

HOW TO CITE THIS ARTICLE

Kajjari S, K VB, Janardhanan S, Antimicrobial Efficacy of , , and Chlorhexidine Mouthwashes on and in Children: A Comparative Study. Int J Clin Pediatr Dent 2024;17(S-1):S78-S83.

摘要

背景

草药在抑制龋齿方面具有促进和预防作用。大多数常用的天然植物提取物,如芒果()和薄荷(),单独或一起使用,经科学充分证明对各种口腔健康问题是安全有效的,尤其是在预防龋齿和牙周疾病方面。

目的

本研究旨在比较评估芒果()、薄荷()漱口水和氯己定(CHX)(0.2%)漱口水对儿童口腔变形链球菌()和远缘链球菌()的影响。

材料与方法

通过随机分配,从一所寄宿学校中选取45名年龄在7至10岁之间的健康儿童,男女不限。他们被分为三个研究组,每组15人;第一组-CHX(对照组),第二组-芒果()漱口水组,第三组-薄荷()漱口水组。收集刺激全唾液样本以检测菌落形成单位数量,并培养口腔变形链球菌()和远缘链球菌()。数据制成表格,并采用方差分析(ANOVA)的单因素方差分析、图基(Tukey)真实显著差异(HSD)检验以及邦费罗尼(Bonferroni)和克鲁斯卡尔-沃利斯(Kruskal-Wallis)检验进行统计分析。

结果

芒果(第二组)和薄荷(第三组)漱口水在基线、第14天和第21天期间唾液菌落计数显著降低,对远缘链球菌()影响最小。在三种类型的漱口中,氯己定最为有效;总体上显示出统计学上的显著降低。与芒果()漱口水相比,薄荷()漱口水在口腔变形链球菌()和远缘链球菌()方面显示出统计学上的显著降低,并且与氯己定的效果几乎相当。

结论

两种草药漱口水均能显著降低儿童口腔变形链球菌()和远缘链球菌()数量。因此,它可被视为漱口水的有效成分。它可能作为一种天然抗菌漱口水且无不良影响。

如何引用本文

卡贾里(Kajjari)S、K VB、贾纳丹南(Janardhanan)S等,芒果()、薄荷()和氯己定漱口水对儿童口腔变形链球菌()和远缘链球菌()的抗菌效果:一项比较研究。《国际临床儿科牙科学杂志》2024年;17(S - 1):S78 - S83。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6b/11343991/cf0de5f75f3c/ijcpd-17-s78-g001.jpg

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