Nanobiotechnology laboratory, Department of Biotechnology, University of Mysore, Manasagangotri, Mysuru, Karnataka, 570006, India.
Division of Biological Sciences, School of Science and Technology, University of Goroka, 441, Goroka, Papua New Guinea.
World J Microbiol Biotechnol. 2023 Apr 6;39(6):148. doi: 10.1007/s11274-023-03596-2.
The advances in nanotechnology have shown enormous impacts in environmental technology as a potent weapon for degradation of toxic organic pollutants and detoxification of heavy metals. It is either by in-situ or ex-situ adaptive strategies. Mycoremediation of environmental pollutants has been a success story of the past decade, by employing the wide arsenal of biological capabilities of fungi. Recently, the proficiency and uniqueness of yeast cell surface alterations have encouraged the generation of engineered yeast cells as dye degraders, heavy metal reduction and its recovery, and also as detoxifiers of various hazardous xenobiotic compounds. As a step forward, recent trends in research are towards developing biologically engineered living materials as potent, biocompatible and reusable hybrid nanomaterials. They include chitosan-yeast nanofibers, nanomats, nanopaper, biosilica hybrids, and TiO-yeast nanocomposites. The nano-hybrid materials contribute significantly as supportive stabilizer, and entrappers, which enhances the biofabricated yeast cells' functionality. This field serves as an eco-friendly cutting-edge cocktail research area. In this review, we highlight recent research on biofabricated yeast cells and yeast-based biofabricated molecules, as potent heavy metals, toxic chemical detoxifiers, and their probable mechanistic properties with future application perspectives.
纳米技术的进步在环境技术中显示出了巨大的影响，是降解有毒有机污染物和解毒重金属的有效手段。它可以通过原位或异位适应策略来实现。在过去的十年中，利用真菌广泛的生物能力，真菌的生物修复已经取得了成功的案例。最近，酵母细胞表面改造的熟练程度和独特性促使人们产生了工程酵母细胞，用于染料降解、重金属还原和回收，以及各种有害异生物质的解毒。作为一个前进的步骤，最近的研究趋势是开发具有生物工程功能的活体材料，作为高效、生物兼容和可重复使用的混合纳米材料。这些材料包括壳聚糖-酵母纳米纤维、纳米垫、纳米纸、生物硅 hybrids 和 TiO-酵母纳米复合材料。纳米混合材料作为支持稳定剂和包封剂，显著提高了生物制造酵母细胞的功能。这个领域是一个环保的前沿鸡尾酒研究领域。在这篇综述中，我们强调了最近关于生物制造酵母细胞和基于酵母的生物制造分子的研究，这些酵母细胞和生物制造分子是有效的重金属、有毒化学物质解毒剂，以及它们可能的机械性质及其未来的应用前景。
