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未来 2040 年德国被诊断为 1 型糖尿病的人数预测:基于索赔数据的分析。

Future number of people with diagnosed type 1 diabetes in Germany until 2040: an analysis based on claims data.

机构信息

Biostatistics and Medical Biometry, Medical School OWL, Bielefeld University, Bielefeld, Germany

Department of Statistics, Ludwig Maximilians University Munich, Munchen, Germany.

出版信息

BMJ Open Diabetes Res Care. 2023 Apr;11(2). doi: 10.1136/bmjdrc-2022-003156.

Abstract

INTRODUCTION

We aim to project the number of people with diagnosed type 1 diabetes in Germany between 2010 and 2040.

RESEARCH DESIGN AND METHODS

We first estimate the age-specific and sex-specific incidence and prevalence of type 1 diabetes in Germany in 2010 using data from 65 million insurees of the German statutory health insurance. Then, we use the illness-death model to project the prevalence of type 1 diabetes until 2040. We alter the incidence and mortality underlying the illness-death model in several scenarios to explore the impact of possible temporal trends on the number of people with type 1 diabetes.

RESULTS

Applying the prevalence from 2010 to the official population projections of Germany's Federal Statistical Office yields a total number of 252 000 people with type 1 diabetes in Germany in 2040 (+1% compared with 2010). Incorporating different annual trends of the incidence and mortality in the projection model results in a future number of people with type 1 diabetes between 292 000 (+18%) and 327 000 (+32%).

CONCLUSIONS

For the first time in Germany, we provide estimates for the incidence, prevalence, and number of people with diagnosed type 1 diabetes for the whole German population between 2010 and 2040. The relative increase of the people with type 1 diabetes ranges from 1% to 32% in 2040 compared with 2010. The projected results are mainly influenced by temporal trends in the incidence. Ignoring these trends, that is, applying a constant prevalence to population projections, probably underestimates future chronic disease numbers.

摘要

简介

我们旨在预测 2010 年至 2040 年德国确诊 1 型糖尿病患者的人数。

研究设计和方法

我们首先使用德国法定健康保险 6500 万被保险人的数据,估算 2010 年德国 1 型糖尿病的年龄别和性别别发病率和患病率。然后,我们使用疾病死亡模型预测 2040 年 1 型糖尿病的患病率。我们在几个场景中改变疾病死亡模型中的发病率和死亡率,以探讨可能的时间趋势对 1 型糖尿病患者人数的影响。

结果

将 2010 年的患病率应用于德国联邦统计局的官方人口预测,得出德国 2040 年 1 型糖尿病患者总数为 252000 人(比 2010 年增加 1%)。在预测模型中纳入发病率和死亡率的不同年度趋势,导致未来 1 型糖尿病患者人数在 292000 人(增加 18%)至 327000 人(增加 32%)之间。

结论

这是德国首次对 2010 年至 2040 年期间全德人口的 1 型糖尿病发病率、患病率和患者人数进行估计。与 2010 年相比,2040 年 1 型糖尿病患者的相对增长率在 1%至 32%之间。预测结果主要受发病率的时间趋势影响。忽略这些趋势,即应用恒定的患病率进行人口预测,可能会低估未来的慢性病人数。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/118e/10083786/e97b87f49662/bmjdrc-2022-003156f01.jpg

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