Biostatistics and Medical Biometry, Medical School OWL, Bielefeld University, Bielefeld, Germany
Department of Statistics, Ludwig Maximilians University Munich, Munchen, Germany.
BMJ Open Diabetes Res Care. 2023 Apr;11(2). doi: 10.1136/bmjdrc-2022-003156.
We aim to project the number of people with diagnosed type 1 diabetes in Germany between 2010 and 2040.
We first estimate the age-specific and sex-specific incidence and prevalence of type 1 diabetes in Germany in 2010 using data from 65 million insurees of the German statutory health insurance. Then, we use the illness-death model to project the prevalence of type 1 diabetes until 2040. We alter the incidence and mortality underlying the illness-death model in several scenarios to explore the impact of possible temporal trends on the number of people with type 1 diabetes.
Applying the prevalence from 2010 to the official population projections of Germany's Federal Statistical Office yields a total number of 252 000 people with type 1 diabetes in Germany in 2040 (+1% compared with 2010). Incorporating different annual trends of the incidence and mortality in the projection model results in a future number of people with type 1 diabetes between 292 000 (+18%) and 327 000 (+32%).
For the first time in Germany, we provide estimates for the incidence, prevalence, and number of people with diagnosed type 1 diabetes for the whole German population between 2010 and 2040. The relative increase of the people with type 1 diabetes ranges from 1% to 32% in 2040 compared with 2010. The projected results are mainly influenced by temporal trends in the incidence. Ignoring these trends, that is, applying a constant prevalence to population projections, probably underestimates future chronic disease numbers.
我们旨在预测 2010 年至 2040 年德国确诊 1 型糖尿病患者的人数。
我们首先使用德国法定健康保险 6500 万被保险人的数据,估算 2010 年德国 1 型糖尿病的年龄别和性别别发病率和患病率。然后,我们使用疾病死亡模型预测 2040 年 1 型糖尿病的患病率。我们在几个场景中改变疾病死亡模型中的发病率和死亡率,以探讨可能的时间趋势对 1 型糖尿病患者人数的影响。
将 2010 年的患病率应用于德国联邦统计局的官方人口预测,得出德国 2040 年 1 型糖尿病患者总数为 252000 人(比 2010 年增加 1%)。在预测模型中纳入发病率和死亡率的不同年度趋势,导致未来 1 型糖尿病患者人数在 292000 人(增加 18%)至 327000 人(增加 32%)之间。
这是德国首次对 2010 年至 2040 年期间全德人口的 1 型糖尿病发病率、患病率和患者人数进行估计。与 2010 年相比,2040 年 1 型糖尿病患者的相对增长率在 1%至 32%之间。预测结果主要受发病率的时间趋势影响。忽略这些趋势,即应用恒定的患病率进行人口预测,可能会低估未来的慢性病人数。