Institute for Biometrics and Epidemiology, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research at Heinrich Heine University, Düsseldorf, Germany.
Department of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.
Diabet Med. 2019 Oct;36(10):1217-1225. doi: 10.1111/dme.13902. Epub 2019 Feb 13.
To project the number of people with Type 2 diabetes in Germany between 2015 and 2040.
Based on data from 65 million insurees of the German statutory health insurance, we projected the age-specific prevalence of diabetes using mathematical relations between prevalence, incidence rate and mortality. We compared several scenarios regarding temporal trends in the incidence and mortality rate. The projected age-specific prevalence was applied to the projected age structure of the German population between 2015 and 2040 to calculate the number of people with Type 2 diabetes.
Application of current age-specific prevalence estimates to the projected age structure in 2040, although ignoring temporal trends in incidence and mortality, yielded an increase in the number of Type 2 diabetes cases from 6.9 million in 2015 to 8.3 million (+21%) in 2040. More realistic scenarios that account for decreasing mortality rates and different trends in the incidence rates project between 10.7 million (+54%) and 12.3 million (+77%) Type 2 diabetes cases in 2040.
For the first time, we projected the number of future Type 2 diabetes cases for the whole adult population in Germany. The results indicate a relative increase in the number of Type 2 diabetes cases of between 54% and 77% from 2015 to 2040. Temporal trends in the incidence rate are the main drivers of this increase. Simply applying current age-specific prevalence to the future age structure probably underestimates the future number of Type 2 diabetes cases.
预测 2015 年至 2040 年期间德国 2 型糖尿病患者的人数。
基于德国法定健康保险 6500 万被保险人的数据,我们使用患病率、发病率和死亡率之间的数学关系预测糖尿病的年龄特异性患病率。我们比较了几种关于发病率和死亡率时间趋势的情景。将预测的年龄特异性患病率应用于 2015 年至 2040 年期间德国人口的预测年龄结构,以计算 2 型糖尿病患者的人数。
尽管忽略了发病率和死亡率的时间趋势,但将当前年龄特异性患病率估计应用于 2040 年的预测年龄结构,2040 年 2 型糖尿病病例数从 2015 年的 690 万增加到 830 万(增加 21%)。考虑到死亡率下降和发病率趋势不同的更现实情景,2040 年预计有 1070 万(增加 54%)至 1230 万(增加 77%)例 2 型糖尿病病例。
我们首次预测了德国所有成年人口未来 2 型糖尿病病例的数量。结果表明,2015 年至 2040 年期间,2 型糖尿病病例的相对数量增加了 54%至 77%。发病率的时间趋势是这种增加的主要驱动因素。简单地将当前的年龄特异性患病率应用于未来的年龄结构可能低估了未来 2 型糖尿病病例的数量。