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斑秃:疾病负担、治疗方法及当前未满足的需求

Alopecia Areata: Burden of Disease, Approach to Treatment, and Current Unmet Needs.

作者信息

Alhanshali Lina, Buontempo Michael G, Lo Sicco Kristen I, Shapiro Jerry

机构信息

Department of Dermatology, SUNY Downstate College of Medicine, Brooklyn, NY, USA.

Department of Dermatology, Hackensack Meridian School of Medicine, Nutley, NJ, USA.

出版信息

Clin Cosmet Investig Dermatol. 2023 Mar 31;16:803-820. doi: 10.2147/CCID.S376096. eCollection 2023.

Abstract

Alopecia areata is an autoimmune hair loss disorder with variations in distribution, duration, and severity. The disease is chronic and often follows an unpredictable course, frequently leading to stress and anxiety for those who suffer from it. Throughout the years more knowledge has been gained regarding pathogenesis, diagnostic tools, impact on quality of life, as well as treatment strategies for alopecia areata. However, challenges in treating and alleviating the burden of disease remain. In this article, we discuss updates regarding the pathogenesis and treatment of alopecia areata and highlight unmet needs of the condition, including a review of limitations of current treatments, accessibility to management strategies, and the need for disease awareness and advocacy.

摘要

斑秃是一种自身免疫性脱发疾病,在分布、持续时间和严重程度上存在差异。这种疾病是慢性的,病程往往不可预测,常常给患者带来压力和焦虑。多年来,人们对斑秃的发病机制、诊断工具、对生活质量的影响以及治疗策略有了更多的了解。然而,在治疗和减轻疾病负担方面仍然存在挑战。在本文中,我们讨论斑秃发病机制和治疗方面的最新进展,并强调该疾病尚未满足的需求,包括对当前治疗局限性的综述、管理策略的可及性,以及提高疾病认知和宣传的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/394e/10072216/667b44621469/CCID-16-803-g0001.jpg

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